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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Susceptibility to Crohn’s disease, a complex inflammatory disease involving the small intestine, is controlled by over 30 loci. One Crohn’s disease risk allele is in ATG16L1, a gene homologous to theExpand
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Incidence of Clostridium difficile infection in inflammatory bowel disease.
BACKGROUND & AIMS Clostridium difficile-associated disease (CDAD) rates have been increasing. We sought to determine whether CDAD incidence has increased specifically in hospitalized patients withExpand
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Outcomes of Clostridium difficile infection in hospitalized leukemia patients: a nationwide analysis.
BACKGROUND The incidence of Clostridium difficile infection (CDI) has increased among hospitalized patients and is a common complication of leukemia. We investigated the risks for and outcomes of CDIExpand
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Risk of Arterial Thrombotic Events in Inflammatory Bowel Disease
OBJECTIVES:Patients with inflammatory bowel disease (IBD) have an increased risk of venous thrombotic events. The risk of arterial thrombotic events in IBD, however, has been less well characterized.Expand
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Reactive hemophagocytic syndrome complicating the treatment of inflammatory bowel disease
Background and Aims: Reactive hemophagocytic syndrome (RHS) is a rare disease in which inappropriately activated macrophages consume bone marrow‐derived cells. Most cases are associated withExpand
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NOD2 status and human ileal gene expression†‡
Background: NOD2 single nucleotide polymorphisms have been associated with increased risk of ileal Crohn's disease (CD). This exploratory study was conducted to compare ileal mucosal gene expressionExpand
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Language, Culture, and Cognition in Cross-cultural Communication
It is well documented that communication styles and patterns vary across cultures. However, less is known about the process underlying these differences. Understanding why communication patterns varyExpand
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Gut‐enriched Krüppel‐like factor regulates colonic cell growth through APC/β‐catenin pathway
Studies on colorectal carcinogenesis have suggested a critical role of the adenomatous polyposis coli (APC) gene in the development of colorectal cancer. Gut‐enriched Krüppel‐like factor (GKLF) is aExpand
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Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset disease.
BACKGROUND & AIMS The influence of age on the presentation, clinical course, and therapeutic response of patients with adult-onset ulcerative colitis (UC) is understudied. Given potential age-relatedExpand
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The combined effect of maternal smoking and obesity on the risk of preeclampsia
Abstract Aims: Cigarette smoking during pregnancy is associated with a lower risk of preeclampsia, whereas obesity increases the risk of preeclampsia. We sought to assess the combined effect ofExpand
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