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Cutaneous responses to environmental stressors
TLDR
The exposure to environmental pro‐oxidant agents leads to the formation of reactive oxygen species (ROS) and the generation of bioactive molecules that can damage skin cells. Expand
The Magic Velvet Bean of Mucuna pruriens
TLDR
In this review, M. pruriens has been shown to have anti-parkinson and neuroprotective effects, which may be related to its anti-oxidant activity. Expand
Comparative effects between electronic and cigarette smoke in human keratinocytes and epithelial lung cells.
TLDR
Exposure to e-CIG vapors results in far less toxic than exposure to CS, in fact, besides the deleterious effect of flavor and nicotine, even the humectants alone are able to evocate cytokines release. Expand
Scavenger receptor class B type I: a multifunctional receptor
TLDR
The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues, and its expression can be modulated by lipopolysaccharide and oxidative stress. Expand
Hypoxia induces cell damage via oxidative stress in retinal epithelial cells
TLDR
Investigation of the effects of CoCl2 on human retinal epithelium cells suggests that oxidative stress induced by hypoxia might be involved in RD development through the stimulation of two key-events of RD such as neo-angiogenesis and apoptosis. Expand
Skin Damage Mechanisms Related to Airborne Particulate Matter Exposure.
TLDR
Surprisingly, by transition electron microscopy analysis, it is shown that CAPs were able to penetrate skin tissues, contributing to the understanding of the cutaneous pathophysiological mechanisms initiated by CAPs exposure, where oxidative stress and inflammation may play predominant roles. Expand
IL-1β induces GFAP expression in vitro and in vivo and protects neurons from traumatic injury-associated apoptosis in rat brain striatum via NFκB/Ca2+–calmodulin/ERK mitogen-activated protein kinase
TLDR
The NF-kB/Ca(2+)-CaM/ERK signaling pathway is identified as a novel in vivo key regulator of IL-1β-induced astrogliosis which may represent a potential target in neurodegeneration. Expand
Vitamin C Compound Mixtures Prevent Ozone-Induced Oxidative Damage in Human Keratinocytes as Initial Assessment of Pollution Protection
TLDR
Results showed that the mixtures tested were able to protect human keratinocytes from O3-induced cytotoxicity, inhibition of cellular proliferation, decrease the formation of HNE protein adducts, ROS, and carbonyls levels, and observe the decreased activation of the redox sensitive transcription factor NF-kB, which is involved in transcribing pro-inflammatory cytokines. Expand
Scavenger receptor B1 post‐translational modifications in Rett syndrome
TLDR
These findings show for the first time a loss of SRB1 in RTT cells and its relationship with a chronic oxidative stress status. Expand
Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β.
TLDR
VA694, Naproxcinod and Naproxen, at both concentrations analyzed, significantly counteracted the negative effects induced by IL-1β, and suggest that these drugs exert anti-inflammatory and chondroprotective effects on OA chondROcytes. Expand
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