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Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms.
ETHNOPHARMACOLOGICAL RELEVANCE The increasing use of traditional herbal medicines around the world requires more scientific evidence for their putative harmlessness. To this end, a plethora ofExpand
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Key fragmentation patterns of aporphine alkaloids by electrospray ionization with multistage mass spectrometry.
This work reports a detailed study of the fragmentations of aporphine alkaloids by electrospray ionization with multistage mass spectrometry (ESI-MS(n)) in positive mode. In a first step the loss ofExpand
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Cytotoxic aporphine alkaloids from Cassytha filiformis.
Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) andExpand
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Total antioxidant activity of hazelnut skin (Nocciola Piemonte PGI): impact of different roasting conditions.
Abstract The thin brown perisperm (skin) that envelops hazelnut kernels is usually removed after roasting process, leading a phenolic-rich by-product. Principal aim of this work was to characteriseExpand
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Cytotoxic and antitumor potentialities of aporphinoid alkaloids.
Aporphinoids form an important group of plant secondary metabolites. Some of these compounds are used for a long time in traditional medicine for the treatment of various diseases, from benignExpand
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Antitrypanosomal compounds from the leaf essential oil of Strychnos spinosa.
The composition of the essential oil obtained by hydrodistillation of the leaves of Strychnos spinosa (Loganiaceae) was analysed by GC-FID and GC-MS. Out of twenty-two compounds identified in theExpand
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Optimization of extraction of phenolic content from hazelnut shell using response surface methodology
Response surface methodology was applied to predict the optimum conditions for extraction of phenolic compounds in hazelnut shell. The phenolic content in the shell extract was determinedExpand
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Methods applied to the in vitro primary toxicology testing of natural products: state of the art, strengths, and limits.
The present review attempts to build up a comprehensive picture of the major primary techniques used to screen and assess the cytotoxicity of plant complex mixtures. These can be based on metabolicExpand
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Medicinal plants used by Burundian traditional healers for the treatment of microbial diseases.
ETHNOPHARMACOLOGICAL RELEVANCE Infectious diseases represent a serious and worldwide public health problem. They lead to high mortality, especially in non-developed countries. In Burundi, the mostExpand
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Inhibition of myeloperoxidase activity by the alkaloids of Peganum harmala L. (Zygophyllaceae).
ETHNOPHARMACOLOGICAL RELEVANCE Seeds and aerial parts of Peganum harmala L. are widely used in Algeria as anti-inflammatory remedies. Evaluation of Peganum harmala total alkaloids extracts and pureExpand
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