The flavonoid quercetin in disease prevention and therapy: facts and fancies.
- M. Russo, C. Spagnuolo, I. Tedesco, S. Bilotto, G. Russo
- Biology, MedicineBiochemical Pharmacology
- 2012
Genistein and cancer: current status, challenges, and future directions.
- C. Spagnuolo, G. Russo, S. Nabavi
- BiologyAdvances in Nutrition
- 1 July 2015
This review critically analyzes the available literature on the therapeutic role of genistein on different types of cancer, focusing on its chemical features, plant food sources, bioavailability, and safety.
Roles of flavonoids against coronavirus infection
- M. Russo, S. Moccia, C. Spagnuolo, I. Tedesco, G. Russo
- BiologyChemico-Biological Interactions
- 28 July 2020
Anti-inflammatory effects of flavonoids in neurodegenerative disorders.
- C. Spagnuolo, S. Moccia, G. Russo
- BiologyEuropean journal of medicinal chemistry
- 7 September 2017
Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia
- C. Spagnuolo, M. Russo, S. Bilotto, I. Tedesco, B. Laratta, G. Russo
- BiologyAnnals of the New York Academy of Sciences
- 1 July 2012
Considering the low toxicity of the flavonoids toward normal peripheral blood cells, the experimental results are in favor of a potential use of quercetin in adjuvant chemotherapy in CLL or other types of cancer.
Broad targeting of resistance to apoptosis in cancer
- R. Mohammad, I. Muqbil, A. Azmi
- BiologySeminars in Cancer Biology
- 28 April 2015
Exploring death receptor pathways as selective targets in cancer therapy.
- M. Russo, A. Mupo, C. Spagnuolo, G. Russo
- Biology, MedicineBiochemical Pharmacology
- 1 September 2010
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
- K. Block, C. Gyllenhaal, M. Zollo
- BiologySeminars in Cancer Biology
- 1 December 2015
Quercetin: a pleiotropic kinase inhibitor against cancer.
- G. Russo, M. Russo, R. Palumbo
- Biology, ChemistryCancer treatment and research
- 2014
The ability of the molecule to inhibit protein kinases involved in deregulated cell growth in cancer cells is reviewed, and the use of natural or synthetic compounds able to stop, reverse, or delay the process of tumorigenesis in its early stages is reviewed.
Neuroprotective Role of Natural Polyphenols.
- C. Spagnuolo, M. Napolitano, I. Tedesco, S. Moccia, Alfonsina Milito, G. Russo
- BiologyCurrent Topics in Medicinal Chemistry
- 30 June 2016
The therapeutic potential of pure herbal compounds and extracts enriched in polyphenols showing the most promising neuroprotective effects are critically reviewed and an extract derived from elderberry, Sambucus nigra, possessing elevated polyphenolic content and antioxidant capacity to protect neuronal cells against oxidizing agents is presented.
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