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- Publications
- Influence
The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants.
- A. Soto, C. Sonnenschein, K. L. Chung, M. Fernández, N. Olea, F. O. Serrano
- Biology, Medicine
- Environmental health perspectives
- 1 October 1995
Estrogens are defined by their ability to induce the proliferation of cells of the female genital tract. The wide chemical diversity of estrogenic compounds precludes an accurate prediction of… Expand
Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption.
- L. Vandenberg, M. Maffini, C. Sonnenschein, B. Rubin, A. Soto
- Medicine
- Endocrine reviews
- 1 February 2009
In 1991, a group of 21 scientists gathered at the Wingspread Conference Center to discuss evidence of developmental alterations observed in wildlife populations after chemical exposures. There, the… Expand
In vitro molecular mechanisms of bisphenol A action.
- Yelena B Wetherill, B. Akingbemi, +6 authors S. Belcher
- Biology, Medicine
- Reproductive toxicology
- 1 August 2007
Bisphenol A (BPA, 2,2-bis (4-hydroxyphenyl) propane; CAS# 80-05-7) is a chemical used primarily in the manufacture of polycarbonate plastic, epoxy resins and as a non-polymer additive to other… Expand
Estrogenicity of resin-based composites and sealants used in dentistry.
- N. Olea, R. Pulgar, +6 authors C. Sonnenschein
- Chemistry, Medicine
- Environmental health perspectives
- 1 March 1996
We tested some resin-based composites used in dentistry for their estrogenic activity. A sealant based on bisphenol-A diglycidylether methacrylate (bis-GMA) increased cell yields, progesterone… Expand
An updated review of environmental estrogen and androgen mimics and antagonists
- C. Sonnenschein, A. Soto
- Chemistry, Medicine
- The Journal of Steroid Biochemistry and Molecular…
- 1 April 1998
For the last 40 y, substantial evidence has surfaced on the hormone-like effects of environmental chemicals such as pesticides and industrial chemicals in wildlife and humans. The endocrine and… Expand
The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells.
- A. Soto, K. L. Chung, C. Sonnenschein
- Chemistry, Medicine
- Environmental health perspectives
- 1 April 1994
Estrogenic pesticides such as DDT and chlordecone generate deleterious reproductive effects. An "in culture" bioassay was used to assess the estrogenicity of several pesticides. The E-screen test… Expand
Androgenic and estrogenic activity in water bodies receiving cattle feedlot effluent in Eastern Nebraska, USA.
- A. Soto, J. Calabro, +8 authors C. Sonnenschein
- Chemistry, Medicine
- Environmental health perspectives
- 1 March 2004
Studies reveal that surface waters worldwide are contaminated with hormonally active agents, many released from sewage treatment plants. Another potential source of aquatic hormonal contamination is… Expand
Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure.
- T. J. Murray, M. Maffini, A. Ucci, C. Sonnenschein, A. Soto
- Biology, Medicine
- Reproductive toxicology
- 1 April 2007
Exposure of the fetus to excess estrogen is believed to increase the risk of developing breast cancer during adult life. Fetal exposure to low doses of the xenoestrogen bisphenol A resulted in… Expand
p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.
- A. Soto, H. Justicia, J. W. Wray, C. Sonnenschein
- Chemistry, Medicine
- Environmental health perspectives
- 1 May 1991
Alkylphenols are widely used as plastic additives and surfactants. We report the identification of an alkylphenol, nonylphenol, as an estrogenic substance released from plastic centrifuge tubes. This… Expand
Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.
- L. Vandenberg, M. Maffini, Perinaaz R. Wadia, C. Sonnenschein, B. Rubin, A. Soto
- Biology, Medicine
- Endocrinology
- 2007
Humans are routinely exposed to bisphenol-A (BPA), an estrogenic compound that leaches from dental materials, food and beverage containers, and other plastic consumer products. Effects of perinatal… Expand