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Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Lampreys are representatives of an ancient vertebrate lineage that diverged from our own ∼500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) genome is… Expand
Essential role of mitochondrial energy metabolism in Foxp3+ T‐regulatory cell function and allograft survival
- U. Beier, A. Angelin, +13 authors W. Hancock
- Medicine, Biology
- FASEB journal : official publication of the…
- 13 February 2015
Conventional T (Tcon) cells and Foxp3+ T‐regulatory (Treg) cells are thought to have differing metabolic requirements, but little is known of mitochondrial functions within these cell populations in… Expand
Goal-directed ultrasound in the detection of long-bone fractures.
BACKGROUND New portable ultrasound (US) systems are capable of detecting fractures in the remote setting. However, the accuracy of ultrasound by physicians with minimal ultrasound training is… Expand
Ringer’s ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats
- C. Sims, S. Wattanasirichaigoon, M. Menconi, A. Ajami, M. Fink
- Critical care medicine
- 1 August 2001
ObjectivePyruvate has been shown to be protective in numerous in vitro and in vivo models of oxidant-mediated cellular or organ system injury. Unfortunately, the usefulness of pyruvate as a… Expand
The influence of unit-based nurse practitioners on hospital outcomes and readmission rates for patients with trauma
- D. Morris, Patrick A. Reilly, J. Rohrbach, Georgianna Telford, Patrick Kim, C. Sims
- The journal of trauma and acute care surgery
- 1 August 2012
BACKGROUND With the increased restrictions on resident work hours, hospitals increasingly are relying on advance practice nurses and physician assistants to help meet the patient care demand. We have… Expand
Short simulation training improves objective skills in established advanced practitioners managing emergencies on the ward and surgical intensive care unit.
BACKGROUND Several studies evaluating simulation training in intensive care unit (ICU) physicians have demonstrated improvement in leadership and management skills. No study to date has evaluated… Expand
Detecting intimate partner violence: more than trauma team education is needed.
- C. Sims, D. Sabra, +5 authors E. Datner
- Journal of the American College of Surgeons
- 1 May 2011
BACKGROUND Intimate partner violence (IPV) is an underappreciated cause of morbidity and mortality in female trauma patients. We investigated the impact of a domestic violence education program for… Expand
The surgical revolving door: risk factors for hospital readmission.
BACKGROUND Unplanned hospital readmissions increase healthcare costs and patient morbidity. We sought to identify risk factors associated with early readmission in surgical patients. MATERIALS AND… Expand
Complications of vena cava filters: A comprehensive clinical review
Deep venous thrombosis (DVT) and pulmonary embolism (PE) constitute common preventable causes of morbidity and mortality. Despite the success of aggressive prophylaxis and screening, the occurrence… Expand
Methylene blue and vasoplegia: who, when, and how?
- S. Stawicki, C. Sims, B. Sarani, M. Grossman, V. Gracias
- Mini reviews in medicinal chemistry
- 1 May 2008
Systemic inflammatory response can be associated with clinically significant and, at times, refractory hypotension. Despite the lack of uniform definitions, this condition is frequently called… Expand