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Profiling changes triggered during maturation of dendritic cells: a lipidomic approach
TLDR
The pattern of lipid composition of dendritic cells, a cell type of critical importance in inflammatory and immune responses, is reported to give an extremely rich source of data for evaluating modulation of specific lipid species triggered during DC maturation.
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Lipidomic approach to identify patterns in phospholipid profiles and define class differences in mammary epithelial and breast cancer cells
TLDR
To establish if patterns in the PL profiles of mammary epithelial cells and breast cancer cells differ in relation to degree of differentiation and metastatic potential, PLs were analyzed using a lipidomic approach and showed dramatic alterations in their profile.
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Lipidomic analysis of phospholipids from human mammary epithelial and breast cancer cell lines
TLDR
Results presented in this work will be useful as a starting point to define possible PLs with prospective as biomarkers and disclose metabolic pathways with potential for cancer therapy.
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Oxidation of glycated phosphatidylethanolamines: evidence of oxidation in glycated polar head identified by LC-MS/MS
TLDR
It is identified, for the first time, that oxidation in glycated PEs also occurs in the glycated polar head, leading to the formation of short chain oxidation products due to cleavage in Glycated moiety.
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Photodynamic oxidation of Staphylococcus warneri membrane phospholipids: new insights based on lipidomics.
TLDR
The overall modification in the relative amount of phospholipids and the formation of lipid hydroxides and hydroperoxides indicate the lethal damage caused to photosensitized bacterial cells.
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Identification of 1-palmitoyl-2-linoleoyl-phosphatidylethanolamine modifications under oxidative stress conditions by LC-MS/MS.
TLDR
The identification and separation of isomeric oxidative products with modifications in the sn-2 acyl chain, attributed to long- and short-chain products were identified.
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Structural Characterization of Oxidized Glycerophosphatidylserine: Evidence of Polar Head Oxidation
TLDR
These findings confirm the oxidation of the serine polar head induced by the hydroxyl radical and help understand the biological role of phosphatidylserine oxidation in the apoptotic process and other biological functions.
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Remodeling of liver phospholipidomic profile in streptozotocin-induced diabetic rats.
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Reactivity of Tyr-Leu and Leu-Tyr dipeptides: identification of oxidation products by liquid chromatography-tandem mass spectrometry.
TLDR
Investigation of the oxidation of isomeric peptides tyrosine-leucine and leucine-tyrosine by Fenton reaction suggests that amino acids in the C-terminal position are more prone to oxidation.
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Photooxidation of glycated and non-glycated phosphatidylethanolamines monitored by mass spectrometry.
TLDR
A model, based on mass spectrometry (MS) analysis, is developed to identify photooxidative degradation of selected PE and glycated PEs and advanced glycated photooxidation products may have a deleterious role in the etiology of diabetic retinopathy and in diabetic retinal microvascular complications.
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