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Primary and secondary haemostasis changes related to aging
Life expectancy has increased in many countries as a result the world's population is aging. The projections indicate that the proportion of the elderly in a few decades will increase significantly.… Expand
Study of the interactions between Edaglitazone and Ciglitazone with PPAR&ggr; and their antiplatelet profile
- C. Muñoz-Gutiérrez, C. Sepúlveda, J. Caballero, I. Palomo, E. Fuentes
- Chemistry, Medicine
- Life sciences
- 1 October 2017
ABSTRACT Peroxisome proliferator‐activated receptor &ggr; (PPAR&ggr;) is a ligand‐activated transcription factor with an important role in lipid metabolism, inflammation and cardiovascular diseases.… Expand
Factor structure and psychometric properties of a Spanish version of LibQUAL
Purpose – LibQUAL is a service‐quality assessment instrument developed by the Association of Research Libraries in partnership with Texas State University. Expand
Role of adenosine A2b receptor overexpression in tumor progression.
The adenosine A2b receptor is a G-protein coupled receptor. Its activation occurs with high extracellular adenosine concentration, for example in inflammation or hypoxia. These conditions are… Expand
Mechanisms of endothelial dysfunction during aging: Predisposition to thrombosis
One of the risk factors for developing cardiovascular disease (CVD) is aging. In the elderly endothelial dysfunction occurs as altered endothelial ability to regulate hemostasis, vascular tone and… Expand
Spatial analysis for the epidemiological study of cardiovascular diseases: A systematic literature search.
- Carlos A. Mena, C. Sepúlveda, E. Fuentes, Yony M. Ormazábal, I. Palomo
- Geospatial health
- 7 May 2018
Cardiovascular diseases (CVDs) are the primary cause of death and disability in de world, and the detection of populations at risk as well as localization of vulnerable areas is essential for… Expand
Antiplatelet activity of drugs used in hypertension, dyslipidemia and diabetes: Additional benefit in cardiovascular diseases prevention.
Beyond its function in hemostasis, platelets activation has an important role in cardiovascular diseases (CVD) development. There are different clinical conditions that can mediate abnormal platelet… Expand
Buddleja globosa (matico) prevents collagen-induced platelet activation by decreasing phospholipase C-gamma 2 and protein kinase C phosphorylation signaling
- Manuel Fuentes, C. Sepúlveda, M. Alarcón, I. Palomo, E. Fuentes
- Biology, Medicine
- Journal of traditional and complementary medicine
- 19 March 2017
Platelets play a key role in thrombosis and cardiovascular diseases. Medicinal plants could be one of the most important factors that influence risks for platelet activation. Buddleja globosa (known… Expand
An empirical model for preliminary seismic response estimation of free-plan nominally symmetric buildings using ANFIS
Abstract The good seismic performance of free-plan buildings during the last Mw = 8.8, February 27, 2010 Chile earthquake, deserves special attention in order to understand the clues for such… Expand
Impact of walkability with regard to physical activity in the prevention of diabetes.
- Carlos A. Mena, C. Sepúlveda, Yony M. Ormazábal, E. Fuentes, I. Palomo
- Geography, Medicine
- Geospatial health
- 3 November 2017
Walkability, a component of urban design intended to facilitate pedestrian traffic, depends on parameters associated with the connectivity of routes, population density and availability of… Expand