• Publications
  • Influence
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies haveExpand
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Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and
  • Leandra Ziad A Zargar Abdul Niveen M Benjamin Cecilia Robe Abarca-Gómez Abdeen Hamid Abu-Rmeileh Acosta-Cazar, Leandra Abarca-Gómez, +1,022 authors M. Ezzati
  • Medicine
  • The Lancet
  • 16 December 2017
Summary Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwideExpand
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Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 controls (phase 1). InExpand
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conducted a multiancestry genome-wide-association meta-analysis in 521,612 individuals (67,162 cases andExpand
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Cohort profile: the study of health in Pomerania.
Henry Volzke, y Dietrich Alte,1y Carsten Oliver Schmidt, Dorte Radke, Roberto Lorbeer, Nele Friedrich, Nicole Aumann, Katharina Lau, Michael Piontek, Gabriele Born, Christoph Havemann, TillExpand
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Seventy-five genetic loci influencing the human red blood cell
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment, growth retardation and impaired physical capacity. To understand further the genetic factors influencing redExpand
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Four-wave mixing in semiconductor optical amplifiers for frequency conversion and fast optical switching
Four-wave mixing (FWM) in semiconductor optical amplifiers (SOAs) is an important tool for frequency conversion and fast optical switching in all-optical communication networks. We review the mainExpand
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Back Pain in the German Adult Population: Prevalence, Severity, and Sociodemographic Correlates in a Multiregional Survey
Study Design. A population-based cross-sectional multiregion postal survey. Objective. To provide a descriptive epidemiology of the prevalence and severity of back pain in German adults and toExpand
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Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.
IMPORTANCE Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically overlaps with major depressive disorder (MDD) and is therefore an important phenotype for psychiatricExpand
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Health-related behaviour, knowledge, attitudes, communication and social status in school children in Eastern Germany.
Enhancing health literacy is a keystone in health promotion. Yet, most studies on health literacy are limited to functional literacy levels. Furthermore, little evidence is available from children.Expand
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