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The polycystic ovary syndrome per se is not associated with increased chronic inflammation.
OBJECTIVE The syndrome of polycystic ovaries (PCOS) is a known risk factor for type 2 diabetes. It is not known, however, whether the increase in diabetes risk is related to endocrine abnormalitiesExpand
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Low serum testosterone levels are associated with increased risk of mortality in a population-based cohort of men aged 20-79.
AIMS Although the association of low serum testosterone levels with mortality has gained strength in recent research, there are few population-based studies on this issue. This study examined whetherExpand
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Cereal fiber improves whole-body insulin sensitivity in overweight and obese women.
OBJECTIVE Cereal fiber intake is linked to reduced risk of type 2 diabetes in epidemiological observations. The pathogenic background of this phenomenon is unknown. Based on recent findings, weExpand
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Circulating ghrelin levels in patients with polycystic ovary syndrome.
The syndrome of polycystic ovaries (PCOS) is associated with adiposity and metabolic changes predisposing to insulin resistance and diabetes mellitus. Because the recently discovered GH secretagogue,Expand
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A high normal TSH is associated with the metabolic syndrome
Objective  Obesity and insulin resistance are key features of the metabolic syndrome. In euthyroidism, the relationships between TSH and insulin resistance or the metabolic syndrome are less clear.Expand
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Thyroid-stimulating hormone is associated with insulin resistance independently of body mass index and age in women with polycystic ovary syndrome.
BACKGROUND The aim of this study was to evaluate the association between thyroid function, reflected by thyroid-stimulating hormone (TSH) levels, and insulin resistance (IR) in 337 women sufferingExpand
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Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls, and the role of
CONTEXT Besides the measurement of IGF-I, GH suppression during an oral glucose tolerance test is recommended to assess the biochemical status in acromegaly. However, the development of highlyExpand
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Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40
Free fatty acids (FFA) cause a rise in cytosolic free Ca2+ ([Ca2+]i) and stimulate insulin release from pancreatic beta-cells. The G-protein coupled receptor GPR40 can be activated by medium- andExpand
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Long-term outcome in patients with acromegaly: analysis of 1344 patients from the German Acromegaly Register.
BACKGROUND Acromegaly is a rare disease with significant morbidity and increased mortality. Epidemiological data about therapeutic outcome under 'real life' conditions are scarce. OBJECTIVE ToExpand
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Activating mutations in the calcium‐sensing receptor: genetic and clinical spectrum in 25 patients with autosomal dominant hypocalcaemia – a German survey
Objective  Autosomal dominant hypocalcaemia or hypoparathyroidism is caused by activating mutations of the calcium‐sensing receptor (CaSR). Treatment with calcium and vitamin D often worsensExpand
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