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Development of the first potent and specific inhibitors of endocannabinoid biosynthesis.
- T. Bisogno, M. G. Cascio, +8 authors V. Di Marzo
- Biology, Medicine
- Biochimica et biophysica acta
- 1 February 2006
Enzymes for the biosynthesis and degradation of the endocannabinoid 2-arachidonoyl glycerol (2-AG) have been cloned and are the sn-1-selective-diacylglycerol lipases alpha and beta (DAGLalpha and… Expand
Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga.
- D. Perrine, J. Chenu, P. Georges, J. Lancelot, C. Saturnino, M. Robba
- Biology, Medicine
- Antimicrobial agents and chemotherapy
- 1 February 1995
The first medical cure of Acanthamoeba keratitis was obtained by use of propamidine isethionate. Since then, it has been the basic drug recommended for use in treatment. Because some Acanthamoeba… Expand
Mutagenicity of nitro- and amino-substituted carbazoles in Salmonella typhimurium. I. Monosubstituted derivatives of 9H-carbazole.
Mononitro, monoamino and monoacetamido carbazoles were assayed for mutagenicity in Salmonella typhimurium strains TA1535, TA1538, TA1537, TA1977, TA98 and TA100, with and without the addition of S9… Expand
Reductive Smiles Rearrangement of 1-[(5-Chloro-2-nitrophenyl)- sulfonyl]-1H-pyrrole-2-carbo-hydrazide to 1-Amino-6-chloro-2- (1H-pyrrol-2-yl)benzimidazole
Sequence-selective binding to DNA of bis(amidinophenoxy)alkanes related to propamidine and pentamidine.
- C. Bailly, D. Perrine, J. Lancelot, C. Saturnino, M. Robba, M. Waring
- Chemistry, Medicine
- The Biochemical journal
- 1 April 1997
The DNA sequences targeted by a complete homologous series of aromatic diamidines have been determined at single-nucleotide resolution via protection from cutting by the endonucleases DNase I, DNase… Expand
Silver(I) N-heterocyclic carbene complexes: Synthesis, characterization and antibacterial activity
Abstract Five new silver complexes having bidentate N -heterocyclic carbene ligands were synthesized and characterized by elemental analysis, IR, NMR and mass spectroscopic methods. Four of the… Expand
Efficient Synthesis of 6-Substituted 3-Nitro- and 3-Amino-1,4- dimethylcarbazoles.
In vitro cytotoxicity of carbazole derivatives. V. 9-Halogeno-substituted 5,11-dimethyl-6H-pyrido[3,2-b]carbazoles
Summary Thirty-seven new 5,11-dimethyl-6 H -pyrido[3,2- b ]carbazole derivatives have been synthesized. These compounds are structurally related to the 5,11-dimethyl-6 H -pyrido[4,3- b ]carbazole… Expand
Synthesis of Unsaturated Macrocycles by Ru‐Catalyzed Ring‐Closing Metathesis: A Comparative Study
The activity and stereoselectivity of phosphane- and N-heterocyclic carbene (NHC)-containing ruthenium benzylidene complexes have been evaluated in macrocyclic ring-closing olefin metathesis to… Expand