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Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach.
Escherichia coli is a model laboratory bacterium, a species that is widely distributed in the environment, as well as a mutualist and pathogen in its human hosts. As such, E. coli represents anExpand
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The endocannabinoid system links gut microbiota to adipogenesis
Obesity is characterised by altered gut microbiota, low‐grade inflammation and increased endocannabinoid (eCB) system tone; however, a clear connection between gut microbiota and eCB signalling hasExpand
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Functional Genomic Studies of Uropathogenic Escherichia coli and Host Urothelial Cells when Intracellular Bacterial Communities Are Assembled*
Uropathogenic Escherichia coli (UPEC), the principal cause of urinary tract infection in women, colonizes the gut as well as the genitourinary tract. Studies of mice inoculated with UTI89, aExpand
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The gut microbiota modulates host energy and lipid metabolism in mice[S]
The gut microbiota has recently been identified as an environmental factor that may promote metabolic diseases. To investigate the effect of gut microbiota on host energy and lipid metabolism, weExpand
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Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice
Background Obesity is associated with accumulation of macrophages in white adipose tissue (WAT), which contribute to the development of insulin resistance. Germ-free (GF) mice have reduced adiposityExpand
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Regulation of Serum Amyloid A3 (SAA3) in Mouse Colonic Epithelium and Adipose Tissue by the Intestinal Microbiota
The gut microbiota has been proposed as an environmental factor that affects the development of metabolic and inflammatory diseases in mammals. Recent reports indicate that gut bacteria-derivedExpand
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Intestinal microbiota during infancy and its implications for obesity.
Obesity is a worldwide epidemic, threatening both industrialized and developing countries, and is accompanied by a dramatic increase in obesity-related disorders, including type 2 diabetes mellitus,Expand
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Microbial regulation of SAA3 expression in mouse colon and adipose tissue
Recently, we demonstrated that colonic and adipose expression of SAA3 was modulated by the gut microbiota and Toll-like receptor signaling in mice. We observed that SAA3 was expressed by colonicExpand
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Role of diet and gut microbiota in management of inflammatory bowel disease in an Asian migrant.
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Beyond phylotyping: understanding the impact of gut microbiota on host biology
Microbial constituents of the gut microbiome interact with each other and the host to alter the luminal environment and impact development, motility, and homeostasis of the gut. Powerful methods areExpand
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