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Sodium transport kinetics in erythrocytes from spontaneously hypertensive rats.
Rat erythrocytes with five different amounts of Na+ content have been prepared by using a new, nondetrimental Na+-loading method (net NaHPO4-influx through the anion carrier). This method allowed the… Expand
The beneficial effect of atrial natriuretic peptide on cyclosporine nephrotoxicity.
- G. Capasso, C. Rosati, F. Ciani, D. Giordano, F. Russo, N. D. De Santo
- American journal of hypertension
- 1 March 1990
Nephrotoxicity is the most common and important side effect of cyclosporine (CyA) therapy. It is characterized by a fall in glomerular filtration rate (GFR) and by a decrease in sodium and water… Expand
d-Lysine reduces the non-enzymatic glycation of proteins in experimental diabetes mellitus in rats
Summaryd-Lysine, the non-physiological isomer of l-lysine, can competitively reduce protein non-enzymatic glycation in vitro. To study the effect of d-lysine in vivo, 6–8-week old Sprague-Dawley rats… Expand
Erythrocyte Na+, K+ pump inhibition after saline infusion in essentially hypertensive subjects: effects of canrenone administration.
The effects of a 2-litre isotonic saline infusion, with and without prior oral canrenone (150 mg) administration, on erythrocyte Na+, K+ pump, urinary sodium excretion and arterial pressure were… Expand
Effects of an intravenous saline load on erythrocyte sodium transport in normal human subjects.
The effects of a 2 litre intravenous infusion of saline (0.9% NaCl solution) over 3 h on erythrocyte transmembrane sodium transport were studied in 12 normal human subjects. After saline infusion a… Expand
Acute effects of hemodialysis on erythrocyte sodium fluxes in uremic patients.
The acute effects of both acetate and bicarbonate hemodialysis on erythrocyte transmembrane sodium fluxes were investigated in 15 patients with chronic uremia. We observed a significance (p less than… Expand
Canrenone Prevents Na,K Pump Inhibition Induced by Volume Expansion in Normal Subjects
Canrenone is the main active metabolite of the diuretic and antihypertensive drugs spironolactone and K-canrenoate (1), end competes with aldosterone for a common cytosolic receptor in distal and… Expand
Stimulatory action of endothelin-1 on membrane Na+ transport in vascular smooth muscle cells in culture.
Endothelin-1 was able to induce an immediate and transient increase in cytosolic free Ca2+ concentrations in the A10 cell line of vascular smooth muscle. This was associated with a strong stimulation… Expand
Stimulation of beta‐adrenoceptors inhibits calcium‐dependent potassium‐channels in mouse macrophages
- C. Rosati, P. Hannaert, J. Dausse, P. Braquet, R. Garay
- Chemistry, Medicine
- Journal of cellular physiology
- 1 December 1986
K+ efflux in mouse macrophages exhibited a rate constant (kK) of 0.67 ± 0.04 (h)−1 (mean ± SEM of 16 experiments). This was strongly stimulated by increasing concentrations of the Ca2+ ionophore… Expand
Stimulation of the Na+, K+ Pump and the (Na+, K+, Cl-) Cotransport System by Endothelin‐1 in Cultured Vascular Smooth Muscle Cells: Involvement of Cyclo‐Oxygenase Products
- R. Garay, C. Rosati, M. Braquet, P. E. Chabrier, P. Braquet
- Chemistry, Medicine
- Journal of cardiovascular pharmacology
Summary The effect of endothelin (ET-1) on vascular smooth muscle cell Na+ and K+ regulation was studied in the A10 cultured cell line. In contrast with other vasoconstrictors, ET-1 was able to… Expand