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A gene-expression signature as a predictor of survival in breast cancer.
BACKGROUND A more accurate means of prognostication in breast cancer will improve the selection of patients for adjuvant systemic therapy. METHODS Using microarray analysis to evaluate ourExpand
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Person-centredness in the care of older adults: a systematic review of questionnaire-based scales and their measurement properties
BackgroundPerson-centredness is promoted as a central feature of the long-term care of older adults. Measures are needed to assist researchers, service planners and regulators in assessing thisExpand
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Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behaviour therapy in adolescents with major depression: randomised controlled trial
Objective To determine whether a combination of a selective serotonin reuptake inhibitor (SSRIs) and cognitive behaviour therapy (CBT) together with clinical care is more effective in the short termExpand
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Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre,
Summary Background Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65–70% of patients. We aimed to assessExpand
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Therapist variation within randomised trials of psychotherapy: implications for precision, internal and external validity
Nesting of patients within therapists in psychotherapy trials creates an additional level within the design. The multilevel nature of this design has implications for the precision, internal andExpand
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Feasibility of a ward-based psychological intervention to improve staff and patient relationships in psychiatric rehabilitation settings.
OBJECTIVES Recent inquiries highlight the anti-therapeutic nature of inpatient psychiatric care. We aim to assess the feasibility and potential efficacy of a ward-based psychological intervention toExpand
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Systematic reviews of the effectiveness of day care for people with severe mental disorders: (1) acute day hospital versus admission; (2) vocational rehabilitation; (3) day hospital versus outpatient
UNLABELLED ***ACUTE DAY HOSPITAL VERSUS ADMISSION FOR ACUTE PSYCHIATRIC DISORDERS*** BACKGROUND Inpatient treatment is an expensive way of caring for people with acute psychiatric disorders. It hasExpand
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Cognitive-behavioural therapy and short-term psychoanalytic psychotherapy versus brief psychosocial intervention in adolescents with unipolar major depression (IMPACT): a multicentre, pragmatic,
BACKGROUND Although there are effective psychological treatments for unipolar major depression in adolescents, whether or not one or more of the available therapies maintain reduced depressiveExpand
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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
Summary Background Arthroscopic sub-acromial decompression (decompressing the sub-acromial space by removing bone spurs and soft tissue arthroscopically) is a common surgery for subacromial shoulderExpand
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Survival Benefits from Follow-Up of Patients with Lung Cancer: A Systematic Review and Meta-Analysis
Introduction: The burden of lung cancer is high for patients and carers. Care after treatment may have the potential to impact on this. We reviewed the published literature on follow-up strategiesExpand
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