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Escherichia coli mechanisms of copper homeostasis in a changing environment.
Escherichia coli is equipped with multiple systems to ensure safe copper handling under varying environmental conditions. The Cu(I)-translocating P-type ATPase CopA, the central component in copperExpand
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CopA: An Escherichia coli Cu(I)-translocating P-type ATPase.
The copA gene product, a putative copper-translocating P-type ATPase, has been shown to be involved in copper resistance in Escherichia coli. The copA gene was disrupted by insertion of a kanamycinExpand
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The zntA gene of Escherichia coli encodes a Zn(II)-translocating P-type ATPase.
The first Zn(II)-translocating P-type ATPase has been identified as the product of o732, a potential gene identified in the sequencing of the Escherichia coli genome. This gene, termed zntA, wasExpand
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Molecular analysis of the copper-transporting efflux system CusCFBA of Escherichia coli.
The cus determinant of Escherichia coli encodes the CusCFBA proteins that mediate resistance to copper and silver by cation efflux. CusA and CusB were essential for copper resistance, and CusC andExpand
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Metallic Copper as an Antimicrobial Surface
ABSTRACT Bacteria, yeasts, and viruses are rapidly killed on metallic copper surfaces, and the term “contact killing” has been coined for this process. While the phenomenon was already known inExpand
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BacMet: antibacterial biocide and metal resistance genes database
We introduce a manually curated database of antibacterial biocide- and metal-resistance genes based on an in-depth review of the scientific literature. Expand
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Intracellular copper does not catalyze the formation of oxidative DNA damage in Escherichia coli.
Because copper catalyzes the conversion of H(2)O(2) to hydroxyl radicals in vitro, it has been proposed that oxidative DNA damage may be an important component of copper toxicity. Elimination of theExpand
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Genes involved in arsenic transformation and resistance associated with different levels of arsenic-contaminated soils
BackgroundArsenic is known as a toxic metalloid, which primarily exists in inorganic form [As(III) and As(V)] and can be transformed by microbial redox processes in the natural environment. As(III)Expand
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Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase
In this article, a mechanism of arsenite [As(III)]resistance through methylation and subsequent volatization is described. Heterologous expression of arsM from Rhodopseudomonas palustris was shown toExpand
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Families of soft-metal-ion-transporting ATPases.
Life undoubtedly first arose in waters rich in metal ions. Since most metal ions are toxic in excess, it is reasonable to speculate that metal resistances probably evolved early, predating antibioticExpand
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