• Publications
  • Influence
Determinants of clinical outcome and survival in acromegaly
TLDR
A retrospective analysis of patients treated at the Departments of Endocrinology and Neurosurgery, Auckland Hospital, New Zealand finds the determinants of final outcome following therapy for acromegaly remain uncertain.
Epidemiology of Acromegaly
TLDR
There is an ongoing excess of patients with chronic complications of acromegaly leading to increased morbidity and mortality from the disorder, with observed-to-expected mortality ratios ranging from 1.6-3.3 and only approaching unity in those with growth hormone levels < 2.5 ug/L following treatment.
Long-term treatment outcome in acromegaly.
TLDR
Current evidence suggests that a post-treatment random serum GH <2.5 microg/l and a normal serum IGF-I value defines biochemical cure, which suggests that achieving similar growth hormone levels after treatment also reduces the prevalence of chronic complications of the disorder, which is subsequently reflected in improved mortality.
High prevalence of psychiatric morbidity in a medical intensive care unit.
TLDR
It is hoped that the index of suspicion for psychiatric morbidity can be raised within a medical intensive care unit in order to optimise the clinical management of patients within this setting.
Acromegaly: factors affecting the long term outcome after surgical treatment
TLDR
Survival and clinical status in 105 acromegalic patients followed for up to 24 years after surgery is assessed against serum growth hormone (GH) levels and other factors; relief of presenting symptoms and tumour clearance related to early post-operative GH levels.
Metamorphosis of a Non-Functioning Pituitary Adenoma to Cushing's Disease
TLDR
A 47 year-old woman presenting initially with a large, invasive and recurrent, non-functioning pituitary tumour necessitated a bilateral adrenalectomy to control the hypercortisolism, which resulted in remarkable clinical improvement.
Cribriform Morular Variant of Papillary Thyroid Carcinoma in a Patient with an Incidental Neck Lump: a Case Report and Review of the Literature
TLDR
A case of a young lady with an incidentally discovered right-sided neck nodule on ultrasonography with a diagnosis of CMV-PTC confirmed on thyroidectomy is reported and literature associated with the clinical presentation, imaging characteristics, pathological findings and the association with FAP is reviewed.
Malaria: an audit of 56 cases admitted to a hospital.
TLDR
A 2-year prospective audit on the profile and outcome of malaria cases admitted to a general hospital was performed, finding that a high index of suspicion of malaria must be maintained in the medical evaluation of all patients and in particular, of returning travellers.
Paraganglioma with pulmonary metastases: a case report.
TLDR
A 29-year-old female presented with cervical lymphadenopathy, excision biopsy of which confirmed the diagnosis of paraganglioma, and was investigated for multiple pulmonary nodules noted on her chest roentgenogram.
Credat Emptor - The Sacrosanct Doctor-Patient Relationship.
  • C. Rajasoorya
  • Medicine
    Annals of the Academy of Medicine, Singapore
  • 1 August 2018
TLDR
This editorial is a personal viewpoint on the problems influencing the doctor-patient relationship, and explores ways of circumventing these.
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