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Optical coherence tomography.
Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.
An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration.
OCT appears useful for determining when retreatment with ranibizumab is necessary, and resulted in visual acuity outcomes similar to the Phase III clinical studies, but required fewer intravitreal injections.
Optical Coherence Tomography
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a
Intravitreal triamcinolone for refractory diabetic macular edema.
Intravitreal triamcinolone is a promising therapeutic method for diabetic macular edema that fails to respond to conventional laser photocoagulation and complications do not appear to be prohibitive.
Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for neovascular age-related macular degeneration.
An intravitreal injection of bevacizumab may provide an effective, safe, and inexpensive option for patients with age-related macular degeneration who are losing vision secondary to macular neovascularization.
Optical coherence tomography of the human retina.
OBJECTIVE To demonstrate optical coherence tomography for high-resolution, noninvasive imaging of the human retina. Optical coherence tomography is a new imaging technique analogous to ultrasound B
Topography of diabetic macular edema with optical coherence tomography.
Optical coherence tomography was a useful technique for quantifying macular thickness in patients with diabetic macular edema and the topographic mapping protocol provided geographic information on macular Thickening that was intuitive and objective.
Transpupillary thermotherapy of occult subfoveal choroidal neovascularization in patients with age-related macular degeneration.
Transpupillary thermotherapy shows no deleterious side effects in treating occult subfoveal choroidal neovascularization and demonstrated decreased exudation on fluorescein angiography, optical coherence tomography, and/or clinical examination.
Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study.
Overall, bevacizumab therapy was well tolerated, with an improvement in VA, OCT, and angiographic outcomes, and although these preliminary results are promising, a randomized controlled clinical trial is necessary before concluding that systemic bevicizumAB therapy is safe and effective for patients with neovascular AMD.
Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography.
Nerve fiber layer thickness can be measured using optical coherence tomography and provide good structural and functional correlation with known parameters, even when controlling for factors associated with the diagnosis of glaucoma.