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Recent Advancements in the Homoallylamine Chemistry.
A Straightforward Synthetic Approach to Antitumoral Pyridinyl Substituted 7H‐Indeno[2,1‐c]quinoline Derivatives via Three‐Component Imino Diels—Alder Reaction.
Recent advancements in the homoallylamine chemistry
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).
- C. Puentes, P. Höcherl, +5 authors B. König
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 June 2011
Aiming at structural optimization of potent and selective ABCG2 inhibitors, such as UR-ME22-1, from our laboratory, an efficient solid phase synthesis was developed to get convenient access to this… Expand
Identification In Silico and In Vitro of Novel Trypanosomicidal Drug‐Like Compounds
- J. Castillo-Garit, Oremia del Toro-Cortés, +9 authors C. Abad
- Biology, Medicine
- Chemical biology & drug design
- 1 July 2012
Atom‐based bilinear indices and linear discriminant analysis are used to discover novel trypanosomicidal compounds. The obtained linear discriminant analysis‐based quantitative structure–activity… Expand
Synthesis and Antiparasitic Properties of New 4‐N‐Benzylamino‐4‐Hetarylbut‐1‐enes
- V. Kouznetsov, J. Castro, +10 authors J. Amaro-Luis
- Chemistry, Medicine
- Archiv der Pharmazie
- 1 January 2005
New derivatives of 4‐N‐benzylamino‐4‐hetarylbut‐1‐ene containing a pyridyl nucleus were synthesized from benzylamines and pyridine aldehydes. N‐oxide derivatives were obtained from these… Expand
A Straightforward Synthetic Approach to Antitumoral Pyridinyl Substituted 7H-Indeno[2,1-c]Quinoline Derivatives Via Three-Component Imino Diels- Alder Reaction
Abstract: A simple and efficient synthetic method of obtaining pyridinyl substituted indeno[2,1- c ]quinolinederivatives has been developed. This method involves a three-component imino Diels-Alder… Expand
Simulation of spirits distillation for a better understanding of volatile aroma compounds behavior: Application to Armagnac production
Abstract A methodology for the simulation of spirits continuous distillation was developed and applied to the analysis of an Armagnac unit, using the software ProSimPlus®. Distillation data for 66… Expand
Review and Thermodynamic Modeling with NRTL Model of Vapor-Liquid Equilibria (VLE) of Aroma Compounds Highly Diluted in Ethanol-Water Mixtures at 101.3 kPa
A review of the vapor–liquid equilibrium data of aroma compounds highly diluted in hydroalcoholic mixtures at 101.3 kPa is presented. The study includes 44 aroma compounds present in distilled… Expand
APLICACION DE LAS REACCIONES DE MULTICOMPONENTES A LA SINTESIS DE INDENO[2,1-c]QUINOLINAS PIRIDIL SUSTITUIDAS Y SINTESIS CONVENCIONAL DE N-(BUTENIL)CLOROALQUILAMIDAS CON FGRAGMENTOS PIRIDINICOS
Las reacciones de multicomponentes, una importante subclase de las reacciones tandem, constan de un proceso ?one-pot? en el cual reaccionan al menos tres componentes que son facilmente asequibles… Expand