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Prematurity and programming of cardiovascular disease risk: a future challenge for public health?
There is substantial epidemiological evidence linking low birth weight with adult cardiometabolic disease risk factors. This has led to the concept of ‘early life programming’ or the ‘developmentalExpand
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Association between preterm brain injury and exposure to chorioamnionitis during fetal life
Preterm infants are susceptible to inflammation-induced white matter injury but the exposures that lead to this are uncertain. Histologic chorioamnionitis (HCA) reflects intrauterine inflammation,Expand
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Prediction of severe retinopathy of prematurity using the WINROP algorithm in a birth cohort in South East Scotland
Purpose We tested the ability of the ‘Weight, IGF-1, Neonatal Retinopathy of Prematurity (WINROP)’ clinical algorithm to detect preterm infants at risk of severe Retinopathy of Prematurity (ROP) in aExpand
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Assessment of Nutritional Status of Children under Five Years of Age, Pregnant Women, and Lactating Women Living in Relief Camps after the Tsunami in Sri Lanka
Background A strong earthquake that hit Aceh on December 26, 2004, triggered a powerful tsunami, resulting in an unprecedented catastrophe in Sri Lanka. The initial phase of the disaster was markedExpand
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Analgesics, sedatives and neuromuscular blockers as part of end-of-life decisions in Dutch NICUs
Verhagen et al 1 describe the use of analgesics, sedatives and neuromuscular blockers (NMBs) during reorientation of care to compassionate measures in Groningen, the Netherlands. The authors drawExpand
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Placental 5-methylcytosine and 5-hydroxymethylcytosine patterns associate with size at birth
Altered placental function as a consequence of aberrant imprinted gene expression may be one mechanism mediating the association between low birth weight and increased cardiometabolic disease risk.Expand
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Dynamic Changes in DNA Methylation Occur during the First Year of Life in Preterm Infants
Background Preterm birth associates with a substantially increased risk of later cardiovascular disease and neurodevelopmental disorders. Understanding underlying mechanisms will facilitate theExpand
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Diffusion MRI parameters of corpus callosum and corticospinal tract in neonates: Comparison between region-of-interest and whole tract averaged measurements
Purpose Measures of white matter (WM) microstructure inferred from diffusion magnetic resonance imaging (dMRI) are useful for studying brain development. There is uncertainty about agreement betweenExpand
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Alterations in glucose concentrations affect DNA methylation at Lrg1 in an ex vivo rat cortical slice model of preterm brain injury
Preterm birth affects 5–18% of all babies and is associated with neurodevelopmental impairment and increased neuropsychiatric disease risk. Although preterm birth associates with differential DNAExpand
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