• Publications
  • Influence
Surface antigens of human embryonic stem cells: changes upon differentiation in culture *
We have analysed the surface antigen phenotype of a human embryonic stem (hES) cell line (H7) and the changes that occur upon differentiation induced by retinoic acid, hexamethylene bisacetamide and
The human embryonal carcinoma marker antigen TRA-1-60 is a sialylated keratan sulfate proteoglycan.
It is indicated that human EC cells generally express a cell surface sialylated keratan sulfate proteoglycan that is subject to modification to yield a variety of epitopes, one of which is recognized by the monoclonal antibody TRA-1-60.
Hybrids of pluripotent and nullipotent human embryonal carcinoma cells: Partial retention of a pluripotent phenotype
The mechanisms that restrict the differentiation capacity of the nullipotent 2102Ep line are complex and include both recessive and dominant acting factors.
The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells
Cadherin-mediated cell adhesion does not appear to play a role in maintaining an EC phenotype, but culture at both low cell density and in the absence of Ca2+ did result in changes in the patterns of cadherin expression suggesting a feedback regulatory effect of cell-to-cell adhesion.
Is intermittent energy restriction effective for weight loss in obese patients?
The primary outcomes of functional ability and pain were assessed by the participants via the RMDQ, a widely used health status measure for low back pain with scores ranging from 0 (no disability) to 24 (most severe), and an 11-point pain scale.