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Nipah virus: a recently emergent deadly paramyxovirus.
Electron microscopic, serologic, and genetic studies indicate that the Nipah virus belongs to the family Paramyxoviridae and is most closely related to the recently discovered Hendra virus, and it is suggested that these two viruses are representative of a new genus within the familyparamyxviridae. Expand
Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness.
A mysterious respiratory illness with high mortality was recently reported in the southwestern United States and nucleotide sequence analysis revealed the associated virus to be a new hantavirus and provided a direct genetic link between infection in patients and rodents. Expand
Junin virus monoclonal antibodies: characterization and cross-reactivity with other arenaviruses.
Cross-reactivity shows the Junin virus to be most closely related to Machupo and Tacaribe viruses, and glycoprotein-specific monoclonal antibodies neutralized JunIn virus to high titres. Expand
The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing.
Phylogenetic analysis indicates that EBO virus subtypes are genetically diverse and that the recent Ivory Coast isolate represents a new (fourth) subtype of EBO Virus, and is virtually identical to the virus that caused a similar epidemic in Yambuku, Zaire almost 20 years earlier. Expand
Climate and satellite indicators to forecast Rift Valley fever epidemics in Kenya.
Analysis of this record and Pacific and Indian Ocean sea surface temperature anomalies, coupled with satellite normalized difference vegetation index data, shows that prediction of Rift Valley fever outbreaks may be made up to 5 months in advance of outbreaks in East Africa. Expand
Long-Term Studies of Hantavirus Reservoir Populations in the Southwestern United States: A Synthesis
A series of intensive, longitudinal, mark-recapture studies of hantavirus infection dynamics in reservoir populations in the southwestern United States indicates consistent patterns as well asExpand
Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations
The etymological derivation of individual names, their pronunciation, and their correct use are explained, and demarcation criteria for each taxon and virus are elaborate. Expand
Genetic Diversity among Lassa Virus Strains
The phylogenetic analyses of full-length NP, GP1, and GP2 gene sequences suggested that Nigerian strains of Lassa virus were ancestral to strains from Guinea, Liberia, and Sierra Leone, suggesting that LassA and the other Old World arenaviruses have either undergone a shorter period of diverisification or are evolving at a slower rate. Expand
Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus*
  • S. Devaraj, Nan Wang, +8 authors Kui Li
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2 November 2007
It is shown here that infection of SARS-CoV triggers a weak IFN response in cultured human lung/bronchial epithelial cells without inducing the phosphorylation of IFN-regulatory factor 3 (IRF-3), a latent cellular transcription factor that is pivotal for type I IFN synthesis. Expand