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"Strong" hydrogen bonds in chemistry and biology.
Although it has been proposed that strong, short, low-barrier hydrogen bonds are important in enzymatic reactions, it is concluded that the evidence for them in small molecules and in biomolecules is inconclusive. Expand
Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant
Evidence is provided which demonstrates that a tricyclic antidepressant can regulate steady-state mRNA levels in vivo by a mechanism which is independent of its effects on synaptic monoamine levels. Expand
Multisite kinetics by quantitative two-dimensional NMR
Constantes de vitesse site-a-site de l'echange de proton de l'acrylamide (dans l'ethanediol) et du thioacetamide (dans le glycerol-DMSO-D 6 )
The origin of the anomeric effect: conformational analysis of 2-methoxy-1,3-dimethylhexahydropyrimidine
The anomeric effect is thought to be the result of either molecular orbital interactions, which stabilize the axial conformer, or electrostatic interactions, which destabilize the equatorial. To testExpand
Multicomponent NMR titration for simultaneous measurement of relative pKaS.
An NMR titration method has been developed to simultaneously measure the difference in acid dissociation constants (delta pKa) of two or more compounds with high precision and accuracy and to demonstrate the utility of this method. Expand
Direct observation of β-chloride elimination from an isolable β-chloroalkyl complex of square-planar nickel.
Kinetic analysis of NiCl(CCl2CCl3)(CNAr(Mes2))2 decomposition indicates that β-chloride (β-Cl) elimination proceeds by a unimolecular mechanism that does not require initial dissociation of a CNAr( Mes2) ligand, suggesting that a direct β-Cl elimination pathway is available to four-coordinate, Group 10 metal vinyl chloride polymerization systems. Expand