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Effect of an enhanced medical home on serious illness and cost of care among high-risk children with chronic illness: a randomized clinical trial.
IMPORTANCE Patient-centered medical homes have not been shown to reduce adverse outcomes or costs in adults or children with chronic illness. OBJECTIVE To assess whether an enhanced medical homeExpand
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Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial
Importance Hypothermia initiated at less than 6 hours after birth reduces death or disability for infants with hypoxic-ischemic encephalopathy at 36 weeks’ or later gestation. To our knowledge,Expand
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Does Aggressive Phototherapy Increase Mortality while Decreasing Profound Impairment among the Smallest and Sickest Newborns?
Objective:Aggressive phototherapy (AgPT) is widely used and assumed to be safe and effective for even the most immature infants. We assessed whether the benefits and hazards for the smallest andExpand
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Treatment of Severe Adult Traumatic Brain Injury Using Bone Marrow Mononuclear Cells
Preclinical studies using bone marrow derived cells to treat traumatic brain injury have demonstrated efficacy in terms of blood–brain barrier preservation, neurogenesis, and functional outcomes.Expand
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Thoracic aortic dissection and rupture in conotruncal cardiac defects: A population-based study.
BACKGROUND Although the risk of thoracic aortic dissection and rupture (TAD) is well-known in bicuspid aortic valve (BAV), the risk of TAD in other congenital heart diseases (CHD), particularlyExpand
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Rate of Gestational Diabetes Mellitus and Pregnancy Outcomes in Patients with Chronic Hypertension.
Objective This study aims to determine the rate of gestational diabetes mellitus (GDM) in pregnancies complicated by chronic hypertension and to compare the adverse outcomes in chronic hypertensiveExpand
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Randomized, controlled pilot trial of bupropion for pregnant smokers: challenges and future directions.
OBJECTIVE The aim of the study is to conduct an initial pilot trial evaluating the feasibility, safety, and efficacy of bupropion for smoking cessation in pregnancy. STUDY DESIGN A randomized,Expand
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Large for Gestational Age Infants and Adverse Outcomes among Uncomplicated Pregnancies at Term
Background While traumatic delivery with large for gestational age (LGA; birth weight above 90%) is acknowledged, there is paucity of data regarding other morbidity and mortality associated with LGA.Expand
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Customized vs population‐based growth charts to identify neonates at risk of adverse outcome: systematic review and Bayesian meta‐analysis of observational studies
To compare the effectiveness of customized vs population‐based growth charts for the prediction of adverse pregnancy outcomes.
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Fetal hemodynamic response to aortic valvuloplasty and postnatal outcome: a European multicenter study
Fetal aortic stenosis may progress to hypoplastic left heart syndrome. Fetal valvuloplasty (FV) has been proposed to improve left heart hemodynamics and maintain biventricular (BV) circulation. TheExpand
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