C. Pathak

Publications16
h-index3
Citations23
Highly Influential Citations5
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Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
Acetylation and deacetylation reactions result in biologically important modifications that are involved in normal cell function and cancer development. These reactions, carried out by protein… Expand
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Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding.
The Hox DNA binding domain, the homeodomain, plays critical roles in genetic control of development and cell fate determination. The variable regulatory functions of Hox proteins are accomplished by… Expand
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Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity.
The toxin-antitoxin (TA) systems widely spread among bacteria and archaea are important for antibiotic resistance and microorganism virulence. The bacterial kingdom uses TA systems to adjust the… Expand
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Crystal structure of toxin HP0892 from Helicobacter pylori with two Zn(II) at 1.8 Å resolution
Antibiotic resistance and microorganism virulence have been consistently exhibited by bacteria and archaea, which survive in conditions of environmental stress through toxin–antitoxin (TA) systems.… Expand
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Cellular Membrane Composition Requirement by Antimicrobial and Anticancer Peptide GA-K4.
Naturally occurring antimicrobial peptides important for innate immunity are widely studied for their antimicrobial and anticancer activity. The primary target of these AMPs is believed to be the… Expand
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Induced DNA bending by unique dimerization of HigA antitoxin
The crystal structures of HigA3 antitoxin and DNA-bound HigA3 allow detailed structural insights into the HigBA toxin–antitoxin system of Mycobacterium tuberculosis. The unique dimerization of HigA3… Expand
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Crystal structure of metal-bound toxin from Helicobacter pylori
Alba from Thermoplasma volcanium
Crystal structure of L66S mutant toxin from Helicobacter pylori
Alba from Thermoplasma volcanium belongs to α-NAT's: An insight into the structural aspects of Tv Alba and its acetylation by Tv Ard1.
The Alba superfamily proteins have been regarded as a conserved group of proteins in archaea and eukarya, which have shown to be important in nucleic acid binding, chromatic organization and gene… Expand
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