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Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery.
Acute kidney injury (AKI) is a frequent complication of cardiopulmonary bypass (CPB). The lack of early biomarkers for AKI has impaired our ability to intervene in a timely manner. Urinary neutrophilExpand
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Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis.
BACKGROUND Acute kidney injury (AKI) is common in hospitalized patients. The impact of AKI on long-term outcomes is controversial. STUDY DESIGN Systematic review and meta-analysis. SETTING &Expand
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Biomarkers for the diagnosis and risk stratification of acute kidney injury: a systematic review.
The diagnosis of acute kidney injury (AKI) is usually based on changes in serum creatinine, but such measurements are a poor marker of acute deterioration in kidney function. We performed aExpand
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Urinary interleukin-18 is a marker of human acute tubular necrosis.
BACKGROUND Interleukin-18 (IL-18) is a mediator of ischemic acute tubular necrosis (ATN) in mice. METHODS IL-18 was measured in human urine to determine whether it might serve as a marker of ATN.Expand
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Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis.
BACKGROUND Delayed graft function (DGF) is a common complication of renal transplantation. The short-term consequences of DGF are well known, but the long-term relationship between DGF and patientExpand
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Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit.
Serum creatinine is not an ideal marker of renal function in patients with acute kidney injury (AKI). Previous studies demonstrated that urinary IL-18 is increased in human AKI. Thus, whether urineExpand
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KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury.
In response to the recently released 2012 KDIGO (Kidney Disease: Improving Global Outcomes) clinical practice guideline for acute kidney injury (AKI), the National Kidney Foundation organized a groupExpand
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Cardiovascular Outcomes in the Irbesartan Diabetic Nephropathy Trial of Patients with Type 2 Diabetes and Overt Nephropathy
Context Previously published results of this randomized, double-blind trial showed that high-risk patients with type 2 diabetic nephropathy had better renal protection if they were treated withExpand
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Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: A prospective multicenter study*
Objective: To determine the incidence, severity, and risk factors of acute kidney injury in children undergoing cardiac surgery for congenital heart defects. Design: Prospective observationalExpand
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Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery.
Acute kidney injury (AKI) is a frequent complication of cardiac surgery and increases morbidity and mortality. The identification of reliable biomarkers that allow earlier diagnosis of AKI in theExpand
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