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In vivo and in vitro effects of cadmium on adult rat brain total antioxidant status, acetylcholinesterase, (Na+, K+)-ATPase and Mg2+-ATPase activities: protection by L-cysteine.
- H. Carageorgiou, Vassilios Tzotzes, C. Pantos, C. Mourouzis, Apostolos Zarros, S. Tsakiris
- Chemistry, Medicine
- Basic & clinical pharmacology & toxicology
- 1 March 2004
This study was undertaken in order to investigate a) the short- and long-term in vivo effects of cadmium (Cd) on brain acetylcholinesterase (AChE), (Na+, K+)-ATPase activities in adult rats, b) the… Expand
Thyroid hormone and recovery of cardiac function in patients with acute myocardial infarction: a strong association?
- Ioannis Lymvaios, I. Mourouzis, D. Cokkinos, M. Dimopoulos, S. Toumanidis, C. Pantos
- European journal of endocrinology
- 1 July 2011
OBJECTIVE This study investigated whether changes in thyroid hormone (TH) in plasma are associated with the recovery of cardiac function in patients with acute myocardial infarction (AMI). Previous… Expand
Propylthiouracil-induced hypothyroidism is associated with increased tolerance of the isolated rat heart to ischaemia-reperfusion.
- C. Pantos, V. Malliopoulou, +8 authors D. Cokkinos
- The Journal of endocrinology
- 1 September 2003
The present study investigated the response of the hypothyroid heart to ischaemia-reperfusion. Hypothyroidism was induced in Wistar rats by oral administration of propylthiouracil (0.05%) for 3 weeks… Expand
Long-term thyroid hormone administration reshapes left ventricular chamber and improves cardiac function after myocardial infarction in rats
- C. Pantos, I. Mourouzis, K. Markakis, N. Tsagoulis, Matthew Panagiotou, D. Cokkinos
- Basic Research in Cardiology
- 15 February 2008
Thyroid hormone (TH) is critical for tissue differentiation at early stages of development, induces physiological hypertrophy and regulates the expression of important contractile proteins such as… Expand
Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion?
Although it has long been recognized that thyroid hormone is an effective positive inotrope, its efficacy in supporting hemodynamics in the acute setting of ischaemia and reperfusion (R) without… Expand
Thyroid hormone and phenotypes of cardioprotection
Abstract.Thyroid hormone has multiple effects on the cardiovascular system with important physiological consequences. Several genes that encode important regulatory and structural proteins in the… Expand
Time-dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling.
- C. Pantos, I. Mourouzis, +7 authors D. Cokkinos
- European journal of endocrinology
- 1 April 2007
The present study investigated whether changes in thyroid hormone (TH) signalling can occur after acute myocardial infarction (AMI) with possible physiological consequences on myocardial performance.… Expand
Thyroid hormone improves the mechanical performance of the post-infarcted diabetic myocardium: a response associated with up-regulation of Akt/mTOR and AMPK activation.
- I. Mourouzis, Irini Giagourta, +5 authors C. Pantos
- Metabolism: clinical and experimental
- 1 October 2013
OBJECTIVE Thyroid hormone (TH) is shown to be protective against cardiac and pancreatic injury. Thus, this study explored the potential effects of TH treatment on the functional status of the… Expand
Thyroid Hormone and Cardiac Disease: From Basic Concepts to Clinical Application
Nature's models of regeneration provide substantial evidence that a natural healing process may exist in the heart. Analogies existing between the damaged myocardium and the developing heart strongly… Expand
Changes in Thyroid Hormone Receptors After Permanent Cerebral Ischemia in Male Rats
- A. Lourbopoulos, I. Mourouzis, +10 authors N. Grigoriadis
- Journal of Molecular Neuroscience
- 28 February 2014
Thyroid hormones (TH) and receptors (TRs) may play an important role in the pathophysiology of acute cerebral ischemia. In the present study, we sought to determine whether serum triodothyronine… Expand