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Safety assessment of standardised methanol extract of Cinnamomum burmannii.
MECB did not cause any mortality nor did it cause any abnormalities in the necropsy and histopathology findings of treated rats, and the LD50 for the MECB was found to be more than 2000 mg/kg.
Acute and subchronic oral toxicity of Coriolus versicolor standardized water extract in Sprague-Dawley rats.
Coriolus versicolor water extract did not cause remarkable adverse effect in SD rats and in the single dose acute toxicity and repeated dose 28-day subchronic toxicity studies, there were no significant difference in body weight, relative organ weight, haematological parameters, clinical chemistry, gross pathology and histopathology between treatment and control groups.
Safety assessment of methanol extract of red dragon fruit (Hylocereus polyrhizus): acute and subchronic toxicity studies.
There was no significant difference in body weight, relative organ weight or hematological parameters in the subchronic toxicity study, and biochemical analysis showed some significant changes, including creatinine, globulin, total protein and urea levels.
Apoptosis induced in human breast cancer cell line by Acanthaster planci starfish extract compared to tamoxifen
The Acanthaster planci starfish extract was found to inhibit the growth of MCF-7 cells (IC) and cytotoxic effect and apoptotic effect of tamoxifen was evaluated.
Anti-hyperglycaemic activity of swietenia macrophylla king (meliaceae) seed extracts in normoglycaemic rats undergoing glucose tolerance tests
PE extracts of S. macrophylla seeds showed anti-hyperglycaemic activity on IPGTTs, and gas chromatography mass spectrometry analysis revealed that several compounds, including fucosterol and β-sitosterol, may be responsible for these anti-hypoglycaemic properties.
Toxicity evaluation of a standardised 50% ethanol extract of Orthosiphon stamineus.
Standardised 50% ethanol extract of O. stamineus did not cause any death nor did it cause abnormalities in necropsy and histopathology findings, suggesting this extract could be devoid of any toxic risk.
Antioxidant and Toxicity Studies of 50% Methanolic Extract of Orthosiphon stamineus Benth
From the results, MEOS showed good superoxide radical scavenging, hydroxyl radical scavenge, ferrous ion chelating, and antilipid peroxidation activities and no abnormality of internal organs was observed between treatment and control groups.
Antioxidant and hepatoprotective effects of Murdannia bracteata methanol extract.
  • M. Yam, L. Ang, +7 authors G. Abdullah
  • Chemistry, Medicine
    Journal of acupuncture and meridian studies
  • 1 September 2010
The hepatoprotective effect of M. bracteata methanol extract is most likely due to its antioxidant and free radical scavenging properties.
Evaluation of anti-cancer activity of Acanthester planci extracts obtained by different methods of extraction.
PBS extract exhibited very potent cytotoxic activity against both MCF-7 and HCT-116 cell lines, and the extracts prepared by sequential extraction procedure from dried starfish found to be ineffective, paving the way for further investigation on the peptide composition in the PBS extract of the starfish to discover potential chemotherapeutic agents.