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Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice.
Type XV collagen occurs widely in the basement membrane zones of tissues, but its function is unknown. To understand the biological role of this protein, a null mutation in the Col15a1 gene wasExpand
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Molecular cloning and functional expression of the Penaeus monodon 5-HT receptor.
Serotonin (5-HT) mediates a number of diverse physiological functions in crustaceans by interacting with various 5-HT receptor subtypes. A putative 5-HT receptor cloned from the ovary of the blackExpand
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Inhibition of Taura syndrome virus replication in Litopenaeus vannamei through silencing the LvRab7 gene using double-stranded RNA
Taura syndrome virus (TSV) is a major cause of high mortality in Pacific white shrimp (Litopenaeusvannamei, Lv). Previously, silencing of Penaeus monodon Rab7 (PmRab7) by injecting double-strandedExpand
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Suppression of PmRab7 by dsRNA Inhibits WSSV or YHV Infection in Shrimp
Viral entry into host cells requires endocytosis machineries of the host for viral replication. PmRab7, a Penaeus monodon small GTPase protein, was investigated for its function in vesicularExpand
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A simple one-step method for producing dsRNA from E. coli to inhibit shrimp virus replication.
While dsRNA has been used experimentally to inhibit replication and thus disease caused by several shrimp viruses, it can be tedious, time consuming and costly to produce. Here we describe a simpleExpand
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A Simple and Cost Effective Method to Generate dsRNA for RNAi Studies in Invertebrates
Using an E. coli strain deficient in ribonuclease III activity, we have developed a simple and cost effective in vivo bacterial expression system to generate large amounts of double-stranded RNAExpand
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Molecular cloning and functional characterization of Argonaute-3 gene from Penaeus monodon.
Argonaute (Ago) proteins play a crucial role in the shrimp RNA interference pathway. In this study, we identified and characterized a novel Ago gene from black tiger shrimp, Penaeus monodon. TheExpand
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Improved preventive and curative effects of YHV infection in Penaeus monodon by a combination of two double stranded RNAs
Abstract YHV causes a severe mortality in Penaeus monodon resulting in a high economic loss of shrimp culture industry. Presently, there is no effective means to prevent or cure YHV infection inExpand
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A Tudor staphylococcal nuclease from Penaeus monodon: cDNA cloning and its involvement in RNA interference.
RNA interference (RNAi) plays an important role in an antiviral defense in shrimp. RNAi technology has been extensively used for inhibition of viral replication and studying gene function. However,Expand
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Antiviral effect of PmRab7 knock-down on inhibition of Laem-Singh virus replication in black tiger shrimp.
PmRab7 is a Penaeus monodon small GTPase protein possibly involved in replication of several shrimp viruses. In this study RNA interference (RNAi) using double-stranded RNA (dsRNA) targeting PmRab7Expand
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