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- Publications
- Influence
Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial.
- C. O'connor, D. Whellan, +14 authors I. Piña
- Medicine
- JAMA
- 8 April 2009
CONTEXT
Guidelines recommend that exercise training be considered for medically stable outpatients with heart failure. Previous studies have not had adequate statistical power to measure the effects… Expand
Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry.
- G. Fonarow, W. G. Stough, +7 authors J. Young
- Medicine
- Journal of the American College of Cardiology
- 21 August 2007
OBJECTIVES
We sought to evaluate the characteristics, treatments, and outcomes of patients with preserved and reduced systolic function heart failure (HF).
BACKGROUND
Heart failure with preserved… Expand
Sertraline Treatment of Major Depression in Patients With Acute MI or Unstable Angina
- A. H. Glassman, C. O'connor, +12 authors W. Harrison
- Medicine
- 14 August 2002
Results Sertraline had no significant effect on mean (SD) LVEF (sertraline: baseline, 54% [10%]; week 16, 54% [11%]; placebo: baseline, 52% [13%]; week 16, 53% [13%]), treatment-emergent increase in… Expand
Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure.
- D. Forman, J. Butler, +9 authors H. Krumholz
- Medicine
- Journal of the American College of Cardiology
- 7 January 2004
OBJECTIVES
The goal of this study was to determine the prevalence of worsening renal function (WRF) among hospitalized heart failure (HF) patients, clinical predictors of WRF, and hospital outcomes… Expand
Diuretic strategies in patients with acute decompensated heart failure.
- G. M. Felker, K. Lee, +19 authors C. O'connor
- Medicine
- The New England journal of medicine
- 2 March 2011
BACKGROUND
Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use.
METHODS
In a prospective,… Expand
Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial.
- M. Redfield, H. Chen, +27 authors E. Braunwald
- Medicine
- JAMA
- 27 March 2013
IMPORTANCE
Studies in experimental and human heart failure suggest that phosphodiesterase-5 inhibitors may enhance cardiovascular function and thus exercise capacity in heart failure with preserved… Expand
Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure.
- W. Jiang, J. Alexander, +8 authors C. O'connor
- Medicine
- Archives of internal medicine
- 13 August 2001
BACKGROUND
Patients with congestive heart failure (CHF) may have a high prevalence of depression, which may increase the risk of adverse outcomes.
OBJECTIVE
To determine the prevalence and… Expand
Depression, Heart Rate Variability, and Acute Myocardial Infarction
- R. Carney, J. Blumenthal, +7 authors K. Freedland
- Medicine
- Circulation
- 23 October 2001
Background—Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a… Expand
Coronary bypass surgery with or without surgical ventricular reconstruction.
- R. Jones, E. Velazquez, +9 authors K. Lee
- Medicine
- The New England journal of medicine
- 23 April 2009
BACKGROUND
Surgical ventricular reconstruction is a specific procedure designed to reduce left ventricular volume in patients with heart failure caused by coronary artery disease. We conducted a… Expand
A standardized definition of ischemic cardiomyopathy for use in clinical research.
- G. M. Felker, L. Shaw, C. O'connor
- Medicine
- Journal of the American College of Cardiology
- 16 January 2002
OBJECTIVES
We sought to evaluate the association between the extent of coronary artery disease (CAD) and survival in patients with symptomatic heart failure (HF) and to create the most prognostically… Expand
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