C. O'brien

Publications48
h-index21
Citations7,348
Highly Influential Citations269
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An Improved Diagnostic Evaluation Instrument for Substance Abuse Patients: The Addiction Severity Index
The Addiction Severity Index (ASI) is a structured clinical interview developed to fill the need for a reliable, valid, and standardized diagnostic and evaluative instrument in the field of alcohol… Expand
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New Data from the Addiction Severity Index Reliability and Validity in Three Centers
The Addiction Severity Index (ASI) is a clinical/research instrument which has been in wide use during the past 6 years to assess the treatment problems found in alcohol- and drug-abusing patients.… Expand
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A New Measure of Substance Abuse Treatment Initial Studies of the Treatment Services Review
This paper describes the development and initial testing of the Treatment Services Review (TSR). The TSR is a 5-minute, technician-administered interview that provides a quantitative profile of the… Expand
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Adverse effects of topical antiglaucoma medication. II. The outcome of filtration surgery.
OBJECTIVE To determine the effect of long-term topical antiglaucoma therapy on the results of glaucoma filtration surgery and to relate any differences to the cell population profile of the… Expand
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Similarity of outcome predictors across opiate, cocaine, and alcohol treatments: role of treatment services.
This study examined the patient and treatment factors associated with 6-month outcome in 649 opiate-, alcohol-, and cocaine-dependent (male and female) adults, treated in inpatient and outpatient… Expand
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A Randomized , Double-Blind , Placebo-Controlled , Phase III Study of Filgrastim in Remission Induction and Consolidation Therapy for Adults With De Novo Acute Myeloid Leukemia
The safety and efficacy of filgrastim as an adjunct to acute ery 5 days earlier after induction 1 than those receiving placebo (P Ú .0001). This was accompanied by reductions in myeloid leukemia… Expand
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Effectiveness and Costs of Inpatient versus Day Hospital Cocaine Rehabilitation
We compared the effectiveness and costs of day hospital (DH) versus inpatient (INP) rehabilitation for cocaine dependence. The research subjects were 111 inner city, lower socioeconomic, primarily… Expand
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Abstinent opiate abusers exhibit conditioned craving, conditioned withdrawal and reductions in both through extinction.
Summary Abstinent opiate abusers who have just completed a 30-day treatment program in a Therapeutic Community setting experience intense drug craving and may even experience subjective withdrawal… Expand
  • 218
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Increased Effectiveness of Substance Abuse Treatment: A Prospective Study of Patient‐Treatment “Matching”
An earlier study retrospectively evaluated the effectiveness of six separate substance abuse treatment programs and generated a set of hypotheses for matching patients to the most appropriate… Expand
  • 240
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Conditioned craving and arousal in cocaine addiction: a preliminary report.
Though data collection is still in progress, several significant findings are already apparent from our study of cocaine 'reminders': 1) In the laboratory, detoxified cocaine abusers show a… Expand
  • 142
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