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Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial
To demonstrate the safety and effectiveness of responsive stimulation at the seizure focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically intractable partial
Long-term treatment with responsive brain stimulation in adults with refractory partial seizures
TLDR
This study provides Class IV evidence that for adults with medically refractory partial onset seizures, responsive direct cortical stimulation reduces seizures and improves quality of life over a mean follow-up of 5.4 years.
Neuronal Hypertrophy in the Neocortex of Patients with Temporal Lobe Epilepsy
TLDR
The reduction in neuropil and its associated elements appears to be a primary feature of TLE, which is not secondary to cell loss, and neuronal hypertrophy emerges as a hallmark of this disease.
Health Care Utilization in Patients With Migraine: Demographics and Patterns of Care in the Ambulatory Setting
TLDR
The treatment of migraine affects people of all races and both sexes and Migraineurs suffer both financial losses and impaired quality of life.
Successful ECT treatment for medically refractory nonconvulsive status epilepticus in pediatric patient
TLDR
A 7-year-old pediatric case is described in which ECT was used successfully to treat medically refractory nonconvulsive status epilepticus (NCSE) without complete withdrawal of antiepileptic drugs (AED).
Vagus nerve stimulation therapy for epilepsy in older adults
TLDR
Quality of life scores improved significantly with time and the efficacy, safety, and tolerability of vagus nerve stimulation for refractory epilepsy increased with time.
Correlates of depressive symptoms in patients with obstructive sleep apnea.
TLDR
Depressive symptoms are more common and more severe in women with OSA than in men, and this is consistent with results of previous studies that showed that depression is more common in women in a broad range of settings.
Usefulness of prolonged video-EEG monitoring in the elderly
TLDR
In selected elderly patients, VEEG is useful in establishing the diagnosis of epilepsy, and may change the management of these patients.
Effects of low- and high-intensity exercise on plasma and cerebrospinal fluid levels of ir-β-endorphin, ACTH, cortisol, norepinephrine and glucose in the conscious dog
TLDR
It is concluded that exercise is a physiologic regulator of both peripheral and central neuroendocrine systems and peripheral release of ir-beta-endorphin, ACTH, and cortisol during exercise is dose-related with respect to time and intensity.
Gabapentin‐induced Myoclonus in End‐stage Renal Disease
TLDR
Analysis of the occurrence and clinical features of myoclonus in patients with end‐stage renal disease who were treated with gabapentin showed clear trends in prognosis and disease progression.
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