• Publications
  • Influence
Genome-Wide Patterns of Genetic Variation in Two Domestic Chickens
TLDR
This study provides a framework for genetic and genomic research of domestic chickens and facilitates the domestic chicken as an avian model for genomic, biomedical, and evolutionary studies.
Transcriptomic analyses of regenerating adult feathers in chicken
TLDR
This study significantly increased the understanding of the complex molecular and cellular events in feather development processes and provided a foundation for future studies on the development of other skin appendages.
Evolution in the Drosophila ananassae species subgroup
TLDR
Analysis of Y-chromosomal and mitochondrial haplotypes, shared chromosome arrangements, pre-mating isolation, and hybrid male sterility suggests that these taxa represent a recent evolutionary radiation and may experience substantial gene flow.
The Chicken Frizzle Feather Is Due to an α-Keratin (KRT75) Mutation That Causes a Defective Rachis
TLDR
The results confirmed KRT75 as the F gene, underlying the frizzle feather trait that has a characteristic curled feather rachis and barbs in domestic chickens, and demonstrates the potential of the approach for identifying genetic determinants of feather forms.
Sex Combs are Important for Male Mating Success in Drosophila melanogaster
TLDR
Direct observations and differences in long-term insemination rates show that the loss of the sex comb strongly reduces the ability of males to copulate with females, and detailed analysis of video recordings indicates this effect is not due to changes in the males’ courtship behavior.
Genomic Organization, Transcriptomic Analysis, and Functional Characterization of Avian α- and β-Keratins in Diverse Feather Forms
TLDR
Functional analysis using mutant chicken keratin forms based on those found in the human α-keratin mutation database led to abnormal phenotypes, demonstrating that the chicken can be a convenient model for studying the molecular biology of human keratin-based diseases.
Identification and evolutionary analysis of long non-coding RNAs in zebra finch
TLDR
This study provides the first systematical identification of avian lNCRNAs using ssRNA-seq analysis and offers a resource of embryonically expressed lncRNAs in zebra finch and predicted the biological function of identified lnc RNAs.
Topographical mapping of α- and β-keratins on developing chicken skin integuments: Functional interaction and evolutionary perspectives
  • Ping Wu, C. Ng, C. Chuong
  • Biology
    Proceedings of the National Academy of Sciences
  • 23 November 2015
TLDR
It is suggested that combinations of α- and β-keratin genes contribute to the morphological and structural diversity of different avian skin appendages, with feather-β-keratins conferring more possible composites in building intrafeather architecture complexity, setting up a platform of morphological evolution of functional forms in feathers.
Genetic Basis of Sex-Specific Color Pattern Variation in Drosophila malerkotliana
TLDR
This report investigates the genetic basis of color pattern variation between two allopatric subspecies of Drosophila malerkotliana, a widespread member of the ananassae species subgroup and indicates that different genetic and molecular changes are responsible for the evolution of similar phenotypic traits in different lineages.
Multiple Regulatory Modules Are Required for Scale‐to‐Feather Conversion
  • Ping Wu, Jie Yan, C. Chuong
  • Biology, Environmental Science
    Molecular biology and evolution
  • 1 February 2018
TLDR
These morpho‐regulatory modules were used to diversify archosaur scales and to initiate feather evolution, and the regulatory combination and hierarchical integration may have led to the formation of extant feather forms.
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