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Double-blind study of clozapine dose response in chronic schizophrenia.
OBJECTIVE This study explored the relative efficacy of three different doses of clozapine. METHOD Fifty patients who met Kane et al.'s criteria for treatment-refractory schizophrenia orExpand
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Psychotropic prescription practices in child psychiatric inpatients 9 years old and younger.
OBJECTIVE We set out to examine psychotropic prescribing patterns among inner city children on public assistance admitted to a university-based inpatient service. METHODS A chart review of childrenExpand
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Therapeutic effects of clozapine on tardive dyskinesia
Neuroleptic-induced tardive dyskinesia (TD) negatively impacts the quality of life for persons with schizophrenia. While no satisfactory treatment is available for TD, a growing body of literatureExpand
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Clozapine withdrawal effects and receptor profiles of typical and atypical neuroleptics
Withdrawal effects of neuroleptics have not received much attention. Clozapine withdrawal phenomena have been attributed to psychosis arising from D2 supersensitivity, which is unlikely since it hasExpand
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The effects of clozapine on symptom clusters in treatment-refractory patients.
Preliminary results of a double-blind clozapine study in a population of chronic psychotic patients at a state psychiatric facility are reported. Thirty "treatment-refractory" schizophrenic patientsExpand
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Does akathisia influence psychopathology in psychotic patients treated with clozapine?
BACKGROUND Akathisia has been reported to predict more severe symptoms and poorer treatment response to typical neuroleptics among patients with schizophrenia. Akathisia has also been associated withExpand
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Nicotine addiction in chronic schizophrenic inpatients
27) were adult neuroleptic-medicated inpatients with a DSM-III-R diagnosis of chronic schizophrenia (n = 22) or schizoaffective disorder (n = 5). Paired t tests revealed higher B! than NAARTExpand
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Absence of changes in antidiuretic hormone, angiotensin II, and atrial natriuretic peptide with clozapine treatment of polydipsia-hyponatremia: 2 case reports.
BACKGROUND Polydipsia-hyponatremia is a poorly understood disorder that causes considerable mortality and morbidity. Hyponatremia in polydipsia-hyponatremia has been attributed to disturbances inExpand
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