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Polyphenols: food sources and bioavailability.
TLDR
The nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed, and bioavailability appears to differ greatly between the variousPolyphenols, and the most abundantpolyphenols in the authors' diet are not necessarily those that have the best bioavailability profile. Expand
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies.
TLDR
Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins. Expand
Dietary Polyphenols and the Prevention of Diseases
TLDR
Experimental studies on animals or cultured human cell lines support a role of polyphenols in the prevention of cardiovascular diseases, cancers, neurodegenerative diseases, diabetes, or osteoporosis, but no clear associations have been found between cancer risk and polyphenol consumption. Expand
Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice
TLDR
In case of a moderate or high consumption of orange juice, flavanones may represent an important part of the pool of total polyphenols present in plasma. Expand
Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
TLDR
The antioxidant capacities of quercetin, 3′‐O‐Methylquercet in and some of their conjugated derivatives were compared by the measurement of the conjugate dienes resulting from the Cu2+‐induced oxidation of human LDL. Expand
Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers.
TLDR
In healthy, middle-aged, moderately overweight men, orange juice decreases DBP when regularly consumed and postprandially increases endothelium-dependent microvascular reactivity, suggesting that hesperidin could be causally linked to the beneficial effect of orange juice. Expand
Bioavailability of rutin and quercetin in rats
TLDR
The rate of elimination of quercetin metabolites seems very low, and high plasma concentrations are easily maintained with a regular supply of quERCetin or rutin in the diet. Expand
Absorption and metabolism of polyphenols in the gut and impact on health.
TLDR
The biological properties of both conjugated derivatives and microbial metabolites have rarely been examined and their study will be essential to better assess the health effects of dietary polyphenols. Expand
Plasma metabolites of quercetin and their antioxidant properties.
TLDR
This study shows that ubiquitous quercetin is conjugated in vivo, yielding metabolites that exhibit antioxidant properties, thus the health benefits of flavonoids in foods can be due to the antioxidant properties of their metabolites. Expand
Catechin is metabolized by both the small intestine and liver of rats.
TLDR
The roles of the rat small intestine in the glucuronidation and methylation of flavonoids as well as the role of the liver in sulfation, methylation and biliary excretion are demonstrated. Expand
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