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Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.
TLDR
PURPOSE To quantify changes in choriocapillary density and in thickness of Bruch's membrane, the chhorocapillaris, and the choroid in 95 unpaired, histologically normal human maculae aged 6 to 100 years and in 25 Maculae with advanced age-related macular degeneration. Expand
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Increased expression of angiogenic growth factors in age-related maculopathy
AIMS/BACKGROUND The late stages of age-related maculopathy (ARM), especially neovascular macular degeneration (ARMD), can severely affect central vision and are the main cause of blindness in theExpand
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Histologic features of the early stages of age-related macular degeneration. A statistical analysis.
TLDR
The age distribution, frequency, and correlation among histologic macular changes, including formation of a basal laminar deposit, drusen, and thickening and calcification of Bruch's membrane, were studied by light microscopy. Expand
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Establishment and characterization of primary and metastatic uveal melanoma cell lines
We report on the establishment and characterization of 2 primary (EOM‐3, EOM‐29) and 3 metastatic uveal melanoma cell lines (OMM‐1, OMM‐2, OMM‐3), and further cytogenetic characterization of aExpand
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Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study.
In subretinal neovascularisation capillaries originating from the choriocapillaris must cross Bruch's membrane to reach the subretinal pigment epithelial space. Thus gaps in Bruch's membrane have toExpand
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Clinical and cytogenetic analyses in uveal melanoma.
PURPOSE Uveal melanoma is one of the most frequently occurring primary intraocular malignancies in the Western world. Cytogenetically these tumors are characterized by typical chromosomal losses andExpand
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Prognostic parameters in uveal melanoma: a review.
Histologic cell type, largest tumor diameter and tumor location have traditionally been regarded as the leading predictors of survival for uveal melanoma. Morphological cell typing is, however,Expand
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Morphologic changes in age‐related maculopathy
Age‐related maculopathy (ARM) is a degenerative disorder of the central part of the retina with a rising prevalence in patients 50 years of age and older, and comprises different histopathologicalExpand
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Hereditary X-linked juvenile retinoschisis: a review of the role of Müller cells.
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Human leukocyte antigen class I expression. Marker of poor prognosis in uveal melanoma.
PURPOSE Because the expression of human leukocyte antigen (HLA) antigens is important for immunologic recognition of tumor cells, we determined expression of locus-specific HLA class I antigens inExpand
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