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Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein
The observation that this glycoprotein that binds Ca2+ and has alkaline phosphatase activity is synthesized in chondrocytes and is exported to the extracellular matrix at the time when calcification begins, suggests that it plays a specific role in the process of calcification. Expand
High-performance liquid chromatographic analysis of urinary hydroxylysyl glycosides as indicators of collagen turnover.
Description d'une methode rapide et sensible, impliquant la conversion des groupes amines de l'hydroxylysine en derives fluorescents a l'aide du chlorure de dansyle, avant la separation parExpand
Determination of galactosyl hydroxylysine in urine as a means for the identification of osteoporotic women.
The aim of the work is to assess the predictive values of the method for the identification of post-menopausal osteoporotic women by measuring galactosyl hydroxylysine in urine by HPLC. Expand
High predictivity of galactosyl-hydroxylysine in urine as an indicator of bone metastases from breast cancer.
We measured the urinary excretion of galactosyl-hydroxylysine (GH) and hydroxyproline in two groups of women with breast cancer, with (M+, n = 24) and without (Mo, n = 30) clinical, scintigraphic, orExpand
High-performance liquid chromatographic preparation of galactosyl-hydroxylysine, a specific bone collagen marker.
Galactosyl-hydroxylysine, a specific bone collagen marker, has been prepared directly from human urine samples by high-performance liquid chromatography (HPLC) on a preparative column. The compoundExpand
Urinary β-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone
Measurement of GH in urine provides a simple and noninvasive method for the evaluation of the extent of bone resorption in large groups of subjects and appears to be more specific than urinary hydroxyproline excretion. Expand