C. Mitchell

Publications26
h-index8
Citations232
Highly Influential Citations9
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Diffusible component from the spore surface of the fungus Aspergillus fumigatus which inhibits the macrophage oxidative burst is distinct from gliotoxin and other hyphal toxins.
BACKGROUND The fungus Aspergillus fumigatus, whose spores are present ubiquitously in the air, causes a range of diseases in the human lung. A small molecular weight (< 10 kD) heat stable toxin… Expand
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Enhanced binding of Aspergillus fumigatus spores to A549 epithelial cells and extracellular matrix proteins by a component from the spore surface and inhibition by rat lung lavage fluid
BACKGROUND Aspergillus fumigatus is a pathogenic fungus which causes a range of diseases, particularly in the human lung. The pathological mechanism is unknown but may involve a complex mixture of… Expand
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Purification and characterization of citrate synthase isoenzymes from Pseudomonas aeruginosa.
Two types of citrate synthase (CS) have been purified from Pseudomonas aeruginosa, a 'large' form (CSI) and a 'small' form (CSII). The M(r)s of the CSI and CSII isoenzymes were determined to be… Expand
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Identification of a multienzyme complex of the tricarboxylic acid cycle enzymes containing citrate synthase isoenzymes from Pseudomonas aeruginosa.
  • C. Mitchell
  • Biology, Medicine
  • The Biochemical journal
  • 1 February 1996
A multienzyme complex of tricarboxylic acid cycle enzymes, catalysing the consecutive reactions from fumarate to 2-oxoglutarate, has been identified in extracts of Pseudomonas aeruginosa prepared by… Expand
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Man and his transport behaviour. Part 2a Walking as a means of transport
The article discusses the work of previous researchers who have suggested that walking is a neglected mode of transport and that its significance is often overlooked in transport policies and plans… Expand
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The role of oxygen in the regulation of glucose metabolism, transport and the tricarboxylic acid cycle in Pseudomonas aeruginosa.
The effect of dissolved oxygen concentration on the metabolism of glucose in Pseudomonas aeruginosa was studied with chemostat cultures using both single-step and gradual transitions from either… Expand
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Inhibition of the alveolar macrophage oxidative burst by a diffusible component from the surface of the spores of the fungus Aspergillus fumigatus.
BACKGROUND: Aspergillus fumigatus is a fungus that grows on dead and decaying organic matter in the environment and whose spores are present ubiquitously in the air. The fungus causes a range of… Expand
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Reversible effects of cross‐linking on the regulatory cooperativity of Acinetobacter citrate synthase
Citrate synthase was purified from Acinetobacter calcoaceticus and treated with the cleavable cross‐linking reagent dithiobis(succinimidyl propionate). Cross‐linking of the enzyme resulted in the… Expand
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Proteolysis of Acinetobacter citrate synthase by subtilisin
Citrate synthase from Acinetobacter calcoaceticus was subjected to proteolysis with subtilisin. Although the enzyme proved relatively resistant to inactivation by this treatment, SDS‐polyacrylamide… Expand
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Pseudomonas citrate synthase: purification and characterisation.
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