• Publications
  • Influence
New Approach for Oral Administration of Insulin With Polyalkylcyanoacrylate Nanocapsules as Drug Carrier
Polyalkylcyanoacrylate nanocapsules (mean size 220 nm), composed of spheric polymeric structures, have been used as a drug carrier for insulin. The rate of encapsulation of insulin is 54.9%, and weExpand
  • 345
  • 10
Cellular localization of an embryonic interferon, ovine trophoblastin and its mRNA in sheep embryos during early pregnancy
Summary— The ovine embryo produces an interferon named ovine Trophoblastin (oTP) which is involved in the maternal recognition of pregnancy and ensures the maintenance of progesterone secretion byExpand
  • 104
  • 3
The Effect of Site of Administration in the Gastrointestinal Tract on the Absorption of Insulin from Nanocapsules in Diabetic Rats
Abstract— Isobutylcyanoacrylate nanocapsules have been used as drug carriers for the enteral absorption of insulin. Their absorption has been studied by measuring fasted glycaemia inExpand
  • 106
  • 1
Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine
The enteral absorption of particles has been investigated in the dog using a colloidal drug carrier, polyalkylcyanoacrylate nanocapsules loaded with an iodized oil (Lipiodol), as a tracer for X‐rayExpand
  • 149
  • 1
Biologically active proteins in the venomous glands of the polychaetous annelid, Glycera convoluta Keferstein.
  • C. Michel, B. Keil
  • Biology, Medicine
  • Comparative biochemistry and physiology. B…
  • 15 January 1975
Abstract 1. 1. A group of macromolecular toxins and two proteolytic activities have been characterized in the venom secreted from the venomous gland of Glycera convoluta after their separation byExpand
  • 14
  • 1
Synergistic interaction between vindesine and X-rays in the prenatal development of mice.
The modification of radiation damage by various concentrations of the oncolytic drug vindesine was studied macroscopically, using mouse embryos during the early organogenesis (days eight and nine ofExpand
  • 6
  • 1
Cellular damage and recovery of the early developing mouse eye following low dose irradiation. I. X-rays on day 8 of gestation
The eye region of mouse embryos, irradiated with 90 rad X-rays on day 8 of gestation, was examined 24 h later for cellular damage. Besides the overall developmental retardation, the radiation insultExpand
  • 1
  • 1
Radiation damage in mouse embryos exposed to 1 rad x-rays or negative pions.
Pregnant mice of two different strains (F/A and NMRI) were exposed to 1 rad of whole-body pion- or X-irradiation at day 8 of gestation. Lucanthone (Miracil D), a known radiosensitizer in variousExpand
  • 19
Teratogenic and radiosensitizing effects of misonidazole on mouse embryos.
Teratogenesis, mutagenesis and carcinogenesis are among the most notable radiation effects in man. There is a continued need to find correlation between these biological responses and also to assessExpand
  • 8