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Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.
TLDR
Sugammadex administered at reappearance of T(2) was significantly faster in reversing rocuronium-induced blockade than neostigmine was in reversing cisatracurium- induced block. Expand
Rocuronium (ORG 9426) neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in humans
TLDR
It is concluded that with rocuronium onset and recovery are faster at the laryngealAdductor muscles, but blockade is less intense than at the adductor pollicis. Expand
Telerobotic-assisted laparoscopic hysterectomy for benign and oncologic pathologies: initial clinical experience with 30 patients
TLDR
Robotic surgery can be safely performed in Gynecologic and gynecologic–oncologic surgery with no increase in complication rates and a significant advance is represented by the surgeon’s ergonomic improvement. Expand
Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study.
TLDR
It is shown that the use of neuromuscular blocking drugs in general anaesthesia is associated with an increased risk of postoperative pulmonary complications, and Anaesthetists must balance the potential benefits of neurmuscular blockade against the increasedrisk of postoperatively pulmonary complications. Expand
Antagonism of Low Degrees of Atracurium-induced Neuromuscular Blockade: Dose–Effect Relationship for Neostigmine
TLDR
Reduced doses (10–30 &mgr;g/kg) of neostigmine are effective in antagonizing shallow atracurium block and for successful reversal within 10 min, as little as 20 &mGr; g/kg neostIGmine may be sufficient. Expand
Monitoring neuromuscular block: an update
TLDR
The need to assure supramaximal stimulation, to place the stimulating electrodes correctly and to use appropriate sites for nerve stimulation as well as appropriate stimulation patterns is emphasized. Expand
A kinetic-dynamic model to explain the relationship between high potency and slow onset time for neuromuscular blocking drugs
TLDR
It is concluded that, in the development of a short-acting nondepolarizing neuromuscular blocking drug, agents having an ED95 of 0.1 Μmol/kg or greater appear more promising. Expand
Pharmacokinetics and Pharmacodynamics of Vecuronium and Pancuronium in Anesthetized Children
TLDR
The pharmacokinetics and pharmacodynamics of vecuronium and pancuronium were determined in 12 children undergoing minor surgery under 60% nitrous oxide, 1 MAC halothane anesthesia and no metabolites could be detected in plasma. Expand
Vecuronium neuromuscular blockade at the diaphragm, the orbicularis oculi, and adductor pollicis muscles.
TLDR
Train-of-four stimulation was applied to the phrenic, facial, and ulnar nerves in 16 adult patients anesthetized with alfentanil-propofol-oxygen to determine the relationship among diaphragm, orbicularis oculi, and adductor pollicis blockade. Expand
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