• Publications
  • Influence
Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies.
TLDR
Post hoc meta-analysis of IMPRESS I and II data revealed that men treated with collagenase C. histolyticum showed a mean 34% improvement in penile curvature, and the mean change in Peyronie disease symptom bother score was significantly improved in treated men vs men on placebo. Expand
An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature
TLDR
The ISSM unified definition of lifelong and acquired PE represents the first evidence-based definition for these conditions and will enable researchers to design methodologically rigorous studies to improve the understanding of acquired PE. Expand
International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation.
TLDR
It is suggested that the prevalence of premature ejaculation is considerably lower than previously thought and that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. Expand
Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses.
TLDR
Tadalafil was consistently efficacious across disease severities and etiologies, as well as in patients of all ages, and well tolerated in this patient population. Expand
Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials.
TLDR
In this diverse population, dapoxetine significantly improved all aspects of PE and was generally well tolerated. Expand
Summary of the recommendations on sexual dysfunctions in men.
TLDR
Specific evaluation, treatment guidelines, and algorithms were developed for every sexual dysfunction in men, including erectile dysfunction; disorders of libido, orgasm, and ejaculation; Peyronie's disease; and priapism. Expand
Erectile dysfunction in men receiving methadone and buprenorphine maintenance treatment.
TLDR
Men on MMT, but not BMT, have high prevalence of ED, related to hypogonadism and depression, and Practitioners should screen for sexual dysfunction in men receiving opioid replacement treatment. Expand
An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation.
TLDR
The ISSM definition of lifelong PE represents the first evidence-based definition of PE, and will hopefully lead to the development of new tools and Patient Reported Outcome measures for diagnosing and assessing the efficacy of treatment interventions and encourage ongoing research into the true prevalence of this disorder. Expand
Efficacy and safety of daily tadalafil in men with erectile dysfunction previously unresponsive to on-demand tadalafil.
  • C. Mcmahon
  • Medicine
  • The journal of sexual medicine
  • 1 November 2004
TLDR
Daily tadalafil (10/20 mg) was effective and well tolerated in this study population and is an effective salvage for previous on-demand tadalAFil nonresponders. Expand
An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE)
TLDR
An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE) and best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients. Expand
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