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Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB.
Previously a novel gene was identified that encodes a glucocorticoid-induced leucine zipper (GILZ) whose expression is up-regulated by dexamethasone. This study analyzed the role of GILZ in theExpand
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Dexamethasone-induced thymocyte apoptosis: apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases.
Glucocorticoid hormones (GCH) have been implicated as regulators of T-lymphocyte growth and differentiation. In particular, it has been reported that GCH can induce thymocyte apoptosis. However, theExpand
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Functional characterization of the effect of nimodipine on the calcium current in rat cerebellar granule cells.
1. We investigated the effect of nimodipine on the calcium current in dissociated cerebellar granule cells from 8-day-old rats. We measured the whole cell current and the depolarization-inducedExpand
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Role of Calcium Channels in Heavy Metal Toxicity
  • C. Marchetti
  • Chemistry, Medicine
  • ISRN toxicology
  • 30 January 2013
The role of voltage-dependent Ca channels (VDCC) in the membrane permeation of two toxic metals, lead (Pb) and cadmium (Cd), was studied in mammalian cells. Both metals interact with Ca-bindingExpand
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Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms
TMEM16F is a membrane protein with possible dual function as an ion channel and a phospholipid scramblase. The properties of ion channels associated with TMEM16F and the link between ion channel andExpand
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Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene
Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene
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Automatic morphometric analysis of skeletal muscle fibers in the aging man
A qualitative and quantitative analysis of M. vastus lateralis fibers from 40 male sedentary subjects, ranging in age from 30 to 89 years, was carried out by light and electron microscopy and by anExpand
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Effects of dopamine and noradrenaline on Ca channels of cultured sensory and sympathetic neurons of chick
The effects of noradrenaline and dopamine on voltage-dependent Ca currents were investigated in cultured dorsal root and sympathetic ganglion neurons from chick embryos. At concentrations of 1 to 10Expand
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Pathways of Cadmium Influx in Mammalian Neurons
Abstract: The Influx of the toxic cation Cd2+ was studied in fura 2‐loaded rat cerebellar granule neurons. In cells depolarized with Ca2+‐free, high‐KCI solutions, the fluorescence emission ratio (R)Expand
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Histochemical and ultrastructural aspects of M. vastus lateralis in sedentary old people (age 65–89 years)
SummaryBiopsies for histochemical and ultrastructural studies were taken from the M. vastus lateralis of 45 healthy sedentary men and women aged 65–89 years. With increasing age the histochemicalExpand
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