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Role of leptin in the neuroendocrine response to fasting

It is proposed that regulation of the neuroendocrine system during starvation could be the main physiological role of leptin, and preventing the starvation-induced fall in leptin with exogenous leptin substantially blunts the changes in gonadal, adrenal and thyroid axes in male mice, and prevents the starve-induced delay in ovulation in female mice.
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Adverse metabolic and cardiovascular consequences of circadian misalignment

The findings demonstrate the adverse cardiometabolic implications of circadian misalignment, as occurs acutely with jet lag and chronically with shift work, on metabolic, autonomic, and endocrine predictors of obesity, diabetes, and cardiovascular risk.
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FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.

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The role of adiponectin in cancer: a review of current evidence.

The pathophysiological mechanisms that underlie the association between adiponectin and malignancy in the context of a dysfunctional adipose tissue in obesity are examined and understanding of these mechanisms may be important for the development of preventive and therapeutic strategies against obesity-associated malignancies.
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Mediterranean diet and incidence and mortality of coronary heart disease and stroke in women

74,886 women aged 38‐63 in the Nurses' Health Study, without a history of cardiovascular disease (CVD) and diabetes were followed from 1984 to 2004 and an alternate Mediterranean diet score was computed from dietary data collected through validated food frequency questionnaires administered 6 times during follow-up.
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Circulating irisin in relation to insulin resistance and the metabolic syndrome.

Irisin is associated with increased risk of MetS, cardiometabolic variables, and CVD in humans, indicating either increased secretion by adipose/muscle tissue and/or a compensatory increase of irisin to overcome an underlying irisin resistance in these subjects.
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Dietary Patterns and Risk of Mortality From Cardiovascular Disease, Cancer, and All Causes in a Prospective Cohort of Women

Greater adherence to the prudent pattern may reduce the risk of cardiovascular and total mortality, whereas greater adhere to the Western pattern may increase the risk among initially healthy women.
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Human leptin levels are pulsatile and inversely related to pituitary–ardenal function

High leptin levels in the obese subject were due solely to increased leptin pulse height; all concentration-independent pulsatility parameters were almost identical in the two women, suggesting that leptin pulsatility therefore can be preserved in the obesity.
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Adiponectin and cancer: a systematic review

Recent findings on the association of adiponectin with several malignancies as well as recent data on underlying molecular mechanisms that provide novel insights into the association between obesity and cancer risk are presented.
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Diabetes mellitus and risk of breast cancer: A meta‐analysis

A meta‐analysis of case–control and cohort studies indicates that diabetes is associated with an increased risk of breast cancer.
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