C. Manach

Publications134
h-index59
Citations26,798
Highly Influential Citations929
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Polyphenols: food sources and bioavailability.
TLDR
The nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed, and bioavailability appears to differ greatly between the variousPolyphenols, and the most abundantpolyphenols in the authors' diet are not necessarily those that have the best bioavailability profile. Expand
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies.
TLDR
Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins. Expand
Dietary Polyphenols and the Prevention of Diseases
TLDR
Experimental studies on animals or cultured human cell lines support a role of polyphenols in the prevention of cardiovascular diseases, cancers, neurodegenerative diseases, diabetes, or osteoporosis, but no clear associations have been found between cancer risk and polyphenol consumption. Expand
HMDB 4.0: the human metabolome database for 2018
TLDR
This year's update to the HMDB, HMDB 4.0, represents the most significant upgrade to the database in its history and should greatly enhance its ease of use and its potential applications in nutrition, biochemistry, clinical chemistry, clinical genetics, medicine, and metabolomics science. Expand
Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies.
TLDR
It is time to rethink the design of in vitro and in vivo studies, so that these issues are carefully considered, and the length of human intervention studies should be increased, to more closely reflect the long-term dietary consumption of polyphenols. Expand
Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice
TLDR
In case of a moderate or high consumption of orange juice, flavanones may represent an important part of the pool of total polyphenols present in plasma. Expand
Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
TLDR
The antioxidant capacities of quercetin, 3′‐O‐Methylquercet in and some of their conjugated derivatives were compared by the measurement of the conjugate dienes resulting from the Cu2+‐induced oxidation of human LDL. Expand
How should we assess the effects of exposure to dietary polyphenols in vitro?
TLDR
Human intervention studies have provided clear evidence that dietary polyphenols are at least partly absorbed and that they have the potential to exert biological effects. Expand
Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content
TLDR
The third release of the Phenol-Explorer database is reported, which adds data on the effects of food processing on polyphenol contents in foods, and is the first database on the effect of foodprocessing onpolyphenol content and all data may be traced back to original sources. Expand
Dietary intake of 337 polyphenols in French adults.
TLDR
In intakes of all known individual polyphenols in the French cohort SUpplémentation en VItamines et Minéraux AntioXydants are estimated by using the recently developed database Phenol-Explorer, which contains content values for 502 polyphenol in 452 foods. Expand
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