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Age-Related Decline in Oligodendrogenesis Retards White Matter Repair in Mice
Background and Purpose— Aging is one of the major risk factors for white matter injury in cerebrovascular disease. However, the effects of age on the mechanisms of injury/repair in white matter… Expand
Blockface histology with optical coherence tomography: A comparison with Nissl staining
Spectral domain optical coherence tomography (SD-OCT) is a high resolution imaging technique that generates excellent contrast based on intrinsic optical properties of the tissue, such as neurons and fibers. Expand
Optical coherence tomography visualizes neurons in human entorhinal cortex
Abstract. The cytoarchitecture of the human brain is of great interest in diverse fields: neuroanatomy, neurology, neuroscience, and neuropathology. Traditional histology is a method that has been… Expand
MRI parcellation of ex vivo medial temporal lobe
- J. Augustinack, C. Magnain, M. Reuter, A. Kouwe, D. Boas, B. Fischl
- Psychology, Medicine
- 1 June 2014
We have identified several cytoarchitectonic features in the medial temporal lobe with high resolution ex vivo MRI, including gray matter structures such as the entorhinal layer II 'islands', perirhinallayer II-III columns, presubicular 'clouds', granule cell layer of the dentate gyrus as well as lamina of the hippocampus. Expand
Polarization-sensitive optical coherence tomography of the human brain connectome
The human brain is composed of approximately 100 billion neurons that ‘communicate’ through an intricate network of axons and dendrites.1 The difficulty of tracing these 3D neuronal pathways,… Expand
Holographic laser Doppler ophthalmoscopy.
We report laser Doppler ophthalmoscopic fundus imaging in the rat eye with near-IR heterodyne holography. Sequential sampling of the beat of the reflected radiation against a frequency-shifted… Expand
Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography.
- H. Wang, C. Magnain, S. Sakadžić, B. Fischl, D. Boas
- Computer Science, Medicine
- Biomedical optics express
- 1 December 2017
We develop a systematic method that includes the confocal parameter for modeling the depth profiles of high NA OCT, when the confocation parameter cannot be ignored. Expand
Holographic laser Doppler imaging of microvascular blood flow.
- C. Magnain, A. Castel, +7 authors M. Atlan
- Physics, Medicine
- Journal of the Optical Society of America. A…
- 1 December 2014
We report on local superficial blood flow monitoring in biological tissue from laser Doppler holographic imaging. In time-averaging recording conditions, holography acts as a narrowband bandpass… Expand
as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity
We developed a fully automatic serial sectioning polarization sensitive optical coherence tomography (PSOCT) system to enable volumetric reconstruction of human brain samples with unprecedented sample size and resolution. Expand
En face speckle reduction in optical coherence microscopy by frequency compounding.
We report the use of frequency compounding to significantly reduce speckle noise in optical coherence microscopy, more specifically on the en face images. This method relies on the fact that the… Expand