Author pages are created from data sourced from our academic publisher partnerships and public sources.
Top 100 relevant results, sorted by most influential
Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python
- Krzysztof J. Gorgolewski, C. Burns, +4 authors S. Ghosh
- Computer Science, Medicine
- Front. Neuroinform.
- 1 August 2011
We present Nipype (Neuroimaging in Python: Pipelines and Interfaces), an open-source, community-developed, software package, and scriptable library. Expand
Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI
- S. Landau, D. Harvey, C. Madison, R. Koeppe, T. Initiative
- Psychology, Medicine
- Neurobiology of Aging
- 1 July 2011
The Functional Activities Questionnaire (FAQ) and Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) are frequently used indices of cognitive decline in Alzheimer's disease (AD). The… Expand
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects.
Although beta-amyloid (Abeta) plaques are a primary diagnostic criterion for Alzheimer's disease, this pathology is commonly observed in the brains of non-demented older individuals. To explore the… Expand
Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging.
Although beta-amyloid (Aβ) deposition is a characteristic feature of Alzheimer's disease (AD), this pathology is commonly found in elderly normal controls (NC). The pattern of Aβ deposition as… Expand
Comparing predictors of conversion and decline in mild cognitive impairment
Objective: A variety of measurements have been individually linked to decline in mild cognitive impairment (MCI), but the identification of optimal markers for predicting disease progression remains… Expand
Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease.
The factors driving clinical heterogeneity in Alzheimer's disease are not well understood. This study assessed the relationship between amyloid deposition, glucose metabolism and clinical phenotype… Expand
Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people.
IMPORTANCE Criteria for preclinical Alzheimer disease (AD) propose β-amyloid (Aβ) plaques to initiate neurodegeneration within AD-affected regions. However, some cognitively normal older individuals… Expand
Alzheimer's Disease Neurodegenerative Biomarkers Are Associated with Decreased Cognitive Function but Not β-Amyloid in Cognitively Normal Older Individuals
- M. Wirth, C. Madison, G. Rabinovici, Hwamee Oh, S. Landau, W. Jagust
- Biology, Medicine
- The Journal of Neuroscience
- 27 March 2013
β-Amyloid (Aβ) plaque deposition and neurodegeneration within temporoparietal and hippocampal regions may indicate increased risk of Alzheimer's disease (AD). This study examined relationships… Expand
Aβ Deposition in aging is associated with increases in brain activation during successful memory encoding.
- E. Mormino, Michael G Brandel, C. Madison, Shawn M Marks, S. Baker, W. Jagust
- Medicine, Psychology
- Cerebral cortex
- 1 August 2012
To investigate early effects of beta-amyloid (Aβ) on neuronal function, elderly normal controls (NCs, age range 58-97) were scanned with Pittsburgh Compound-B (PIB) positron emission tomography (a… Expand
Neural compensation in older people with brain β-amyloid deposition
- Jeremy A. Elman, Hwamee Oh, +6 authors W. Jagust
- Medicine, Psychology
- Nature Neuroscience
- 16 August 2014
Recruitment of extra neural resources may allow people to maintain normal cognition despite amyloid-β (Aβ) plaques. Previous fMRI studies have reported such hyperactivation, but it is unclear whether… Expand