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Strategies for Fermentation Medium Optimization: An In-Depth Review
Comparative analysis of the merits and demerits of various conventional as well as modern optimization techniques applied during fermentation process of metabolite production. Expand
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Production of L-phenylacetylcarbinol by fermentation
Abstract In pharmaceutical industry, l -phenylacetylcarbinol ( l -PAC) is used as an intermediate for the production of l -ephedrine hydrochloride—a well known bronchodilator. Certain yeast strainsExpand
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Microbial production of d-amino acids
Abstract The production of d -aminoacylase by Alcaligenes denitrificans and Alcaligenes faecalis has been studied. The enzyme was inducibly produced and N -acetyl- d -leucine and N -acetyl- d -valineExpand
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Microbial heparin/heparan sulphate lyases: potential and applications
Heparin/heparan sulphate glycosaminoglycans (HSGAGs) are composed of linear chains of 20–100 disaccharide units of N-acetylated d-glucosamine α (1–4) linked to glucuronic acid. HSGAGs are widelyExpand
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Coumarin–benzimidazole hybrids as a potent antimicrobial agent: synthesis and biological elevation
Molecular hybridization approach is an emerging tool in drug discovery for designing new pharmacophores with biological activity. A novel, new series of coumarin–benzimidazole hybrids were designed,Expand
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Isolation, Screening, and Identification of Novel Isolates of Actinomycetes from India for Antimicrobial Applications
The search for novel bioactive compounds from the natural environment has rapidly been gaining momentum with the increase in multi-drug resistant (MDR) pathogens. In the present study, theExpand
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Studies on the production of actinomycin‐D by Streptomyces griseoruber– a novel source
Aims:  To isolate and characterize bioactive metabolites produced by a micro‐organism isolated from a soil sample associated with the roots of a medicinal plant, Azadirachta indica.
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Response surface methodology for optimization of medium components in submerged culture of Aspergillus flavus for enhanced heparinase production
Aims:  Aim of the study was to develop a medium for optimal heparinase production with a strain of Aspergillus flavus (MTCC‐8654) by using a multidimensional statistical approach.
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Nutritional regulation of actinomycin-D production by a new isolate of Streptomyces sindenensis using statistical methods.
Production of actinomycin-D, by an isolate, S. sindenensis, was optimized by statistical methods. Fructose peptone and NaNO3 were found to be critical for antibiotic production. In the second step,Expand
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Studies on optimum fermentation conditions for actinomycin-D production by two new strains of Streptomyces spp.
Two biologically active microbial strains were isolated from soil samples collected from different geographical areas of India. These strains were characterized as Streptomyces halstedii MTCC 6817Expand
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