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Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents.
Flavonoids are secondary metabolites abundantly present in commonly consumed fruits and vegetables. They possess diverse properties such as anti-inflammatory, anti-oxidant and anti-cancer.Expand
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Phytotherapy and women's reproductive health: the Cameroonian perspective.
Approximately 80 % of the population in Africa use traditional medicinal plants to improve their state of health. The reason of such a wide use of medicinal plants has been mainly attributed to theirExpand
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Effects of the extracts of some tropical medicinal plants on estrogen inducible yeast and Ishikawa screens, and on ovariectomized Wistar rats.
A total of 33 extracts from 18 Cameroonians plants were studied in two in vitro test systems to determine potential estrogenic activities. The estrogenic activities of the extracts, which have shownExpand
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Effects of Millettia macrophylla (Fabaceae) extracts on estrogen target organs of female wistar rat.
The present study aims to determine the estrogenicity of Millettia macrophylla, a Cameroonian medicinal plant, in ovariectomized rats and to investigate the underlying mechanisms, in order to justifyExpand
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Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.
ETHNOPHARMACOLOGICAL RELEVANCE Crateva adansonii DC is a plant traditionally used in Cameroon to treat constipation, asthma, snakebites, postmenopausal complaints and cancers. AIM The anticancerExpand
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Estrogenic effects of the ethyl-acetate extract of the stem bark of Erythrina lysistemon Hutch (Fabaceae).
The stem bark of Erythrina lysistemon, one of the traditionally used "women remedies", has been assessed for its estrogenic activity. The ethyl-acetate extract of the stem bark of E. lysistemonExpand
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Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells.
Activation of estrogen receptor α (ERα) stimulates cell division and tumor growth by modulating the expression of ERα target genes. This activation involves the recruitment of specific proteins withExpand
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Estrogenic effects of a methanol extract of the fruit of Brenania brieyi de Wild (Rubiaceae)
Fruit of the Cameroonian medicinal tree Brenania brieyi is used in the treatment of endocrine disorders, including menopausal complaints. To assess the potential estrogenicity, 50 mg/kg BW/day of aExpand
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Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents
Flavonoids are secondary metabolites abundantly present in commonly consumed fruits and vegetables. They possess diverse properties such as anti-inflammatory, anti-oxidant and anti-cancer.Expand
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Elucidation of Underlying Mechanisms by Which Millettia macrophylla Benth Induces Its Estrogenic Activity
Millettia macrophylla is used traditionally to treat menopause related symptoms. This plant was shown to exhibit estrogenic effects in vitro on human embryonic kidney cells and in vivo onExpand
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