From Kratom to mitragynine and its derivatives: Physiological and behavioural effects related to use, abuse, and addiction
- Z. Hassan, M. Muzaimi, C. Müller
- Psychology, BiologyNeuroscience and Biobehavioral Reviews
- 1 February 2013
FGF21 Regulates Sweet and Alcohol Preference.
- Saswata Talukdar, B. Owen, S. Kliewer
- Biology, MedicineCell Metabolism
- 9 February 2016
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
- E. Gulbins, M. Palmada, J. Kornhuber
- Psychology, BiologyNature Network Boston
- 1 July 2013
Lowering ceramide abundance may be a central goal for the future development of antidepressants as the role of the acid sphingomyelinase-ceramide system as a target for antidepressants is investigated.
Drugs as instruments: A new framework for non-addictive psychoactive drug use
- C. Müller, G. Schumann
- Psychology, BiologyBehavioral and Brain Sciences
- 10 November 2011
It is argued that drug instrumentalization behavior may provide a functional adaptation to modern environments based on a historical selection for learning mechanisms that allow the dynamic modification of consummatory behavior.
Serotonin and psychostimulant addiction: Focus on 5-HT1A-receptors
- C. Müller, R. Carey, J. Huston, M. A. D. S. Silva
- Biology, PsychologyProgress in neurobiology
- 1 February 2007
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
- G. Schumann, Chunyu Liu, P. Elliott
- MedicineProceedings of the National Academy of Sciences
- 28 November 2016
It is shown that brain-specific β-Klotho KO mice have an increased alcohol preference and that FGF21 inhibits alcohol drinking by acting on the brain, suggesting that a liver–brain endocrine axis may play an important role in the regulation of alcohol drinking behavior and provide a unique pharmacologic target for reducing alcohol consumption.
What's conditioned in conditioned place preference?
- J. Huston, M. A. D. S. Silva, B. Topic, C. Müller
- Psychology, BiologyTIPS - Trends in Pharmacological Sciences
- 1 March 2013
Abuse potential and adverse cognitive effects of mitragynine (kratom)
- N. H. Yusoff, F. W. Suhaimi, C. Müller
- Biology, PsychologyAddiction Biology
- 1 January 2016
Findings provide evidence for an addiction potential with cognitive impairments for mitragynine, which suggest its classification as a harmful drug.
Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users.
- Darshan Singh, C. Müller, B. Vicknasingam
- MedicineDrug and Alcohol Dependence
- 1 June 2014
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.
- S. Nuber, F. Harmuth, O. Riess
- BiologyBrain : a journal of neurology
- 1 February 2013
Ageing promoted conversion of both full-length and C-terminally truncated α-synuclein species into insolube and proteinase K-resistant fibres, with strongest accumulation in the striatum, resembling biochemical changes seen in human Parkinson's disease.
...
...