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Does Multimodal Analgesia with Acetaminophen, Nonsteroidal Antiinflammatory Drugs, or Selective Cyclooxygenase-2 Inhibitors and Patient-controlled Analgesia Morphine Offer Advantages over Morphine…
The authors analyzed data from 52 randomized placebo-controlled trials (4,893 adults) testing acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors given in… Expand
Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials.
Intrathecal morphine without local anaesthetic is often added to a general anaesthetic to prevent pain after major surgery. Quantification of benefit and harm and assessment of dose-response are… Expand
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
CONTEXT Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy. OBJECTIVE To assess whether dexamethasone dose-dependently reduces the risk of… Expand
Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia.
- C. Lysakowski, L. Dumont, M. Pellegrini, F. Clergue, E. Tassonyi
- British journal of anaesthesia
- 1 April 2001
The bispectral index (BIS) and a sedation score were used to determine and compare the effect of propofol in the presence of fentanyl, alfentanil, remifentanil and sufentanil. Seventy-five… Expand
Transcranial Doppler Versus Angiography in Patients With Vasospasm due to a Ruptured Cerebral Aneurysm: A Systematic Review
Background and Purpose— Transcranial Doppler (TCD) is used for diagnosis of vasospasm in patients with subarachnoid hemorrhage due to a ruptured aneurysm. Our aim was to evaluate both the accuracy of… Expand
Time course of rocuronium‐induced neuromuscular block after pre‐treatment with magnesium sulphate: a randomised study
- C. Czarnetzki, C. Lysakowski, N. Elia, M. Tramèr
- Acta anaesthesiologica Scandinavica
- 1 March 2010
Background: A previously published study suggested that pre‐treatment with magnesium sulphate (MgSO4) had no impact on the speed of onset of rocuronium‐induced neuromuscular block. We set out to… Expand
Effect of Perioperative Systemic &agr;2 Agonists on Postoperative Morphine Consumption and Pain Intensity: Systematic Review and Meta-analysis of Randomized Controlled Trials
Background: Systemic &agr;2 agonists are believed to reduce pain and opioid requirements after surgery, thus decreasing the incidence of opioid-related adverse effects, including hyperalgesia.… Expand
Ventilation strategies in obese patients undergoing surgery: a quantitative systematic review and meta-analysis.
- M. Aldenkortt, C. Lysakowski, N. Elia, L. Brochard, M. Tramèr
- British journal of anaesthesia
- 1 October 2012
BACKGROUND Pathophysiological changes due to obesity may complicate mechanical ventilation during general anaesthesia. The ideal ventilation strategy is expected to optimize gas exchange and… Expand
Reappraisal of acetazolamide for the prevention of acute mountain sickness: a systematic review and meta-analysis.
- B. Kayser, L. Dumont, C. Lysakowski, C. Combescure, G. Haller, M. Tramèr
- High altitude medicine & biology
- 22 June 2012
Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically… Expand
Prevention of Succinylcholine-induced Fasciculation and Myalgia: A Meta-analysis of Randomized Trials
Fifty-two randomized trials (5,318 patients) were included in this meta-analysis. In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%. Nondepolarizing… Expand