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The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism
  • C. Lord, S. Risi, +5 authors M. Rutter
  • Psychology, Medicine
  • Journal of autism and developmental disorders
  • 17 October 2000
TLDR
Algorithm sensitivities and specificities for autism and PD DNOS relative to nonspectrum disorders were excellent, with moderate differentiation of autism from PDDNOS. Expand
Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
TLDR
The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria. Expand
Autism Diagnostic Observation Schedule
Autism screening questionnaire: diagnostic validity.
TLDR
The ASQ has good discriminative validity with respect to the separation of PDD from non-PDD diagnoses at all IQ levels, with a cut-off of 15 proving most effective. Expand
Functional impact of global rare copy number variation in autism spectrum disorders
TLDR
The genome-wide characteristics of rare (<1% frequency) copy number variation in ASD are analysed using dense genotyping arrays to reveal many new genetic and functional targets in ASD that may lead to final connected pathways. Expand
The Autism Brain Imaging Data Exchange: Towards Large-Scale Evaluation of the Intrinsic Brain Architecture in Autism
TLDR
W Whole-brain analyses reconciled seemingly disparate themes of both hypo- and hyperconnectivity in the ASD literature; both were detected, although hypoconnectivity dominated, particularly for corticocortical and interhemispheric functional connectivity. Expand
Standardizing ADOS Scores for a Measure of Severity in Autism Spectrum Disorders
TLDR
Calibrated severity scores had more uniform distributions across developmental groups and were less influenced by participant demographics than raw totals and should be useful in comparing assessments across modules and time. Expand
Behavioural phenotyping assays for mouse models of autism
TLDR
Robust phenotypes in mouse models hold great promise as translational tools for discovering effective treatments for components of autism spectrum disorders. Expand
The Autism Diagnostic Observation Schedule: Revised Algorithms for Improved Diagnostic Validity
TLDR
Reflecting recent research, the revised algorithm now consists of two new domains, Social Affect and Restricted, Repetitive Behaviors, combined to one score to which thresholds are applied, resulting in generally improved predictive value. Expand
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